← Return to Anyone have severe bone (spine) loss with recurrence of PC?

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Profile picture for grandpun @grandpun

Had Prolia from start of Lupron. Taking calcium since ending Lupron. DEXA done twice. Before RALP and about 6-months after ADT stopped. I was 70% to the good side for my age, 78.
I’m worried that since sore back didn’t start till just after last PSA, 9/25, that PC has come back super fast deteriorating 3 vertebra.
But never heard PC causing bone loss. Thought it only made tumors.
Worried and confused.
Will request biopsy of bone for PC or other culprit during repair

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Replies to "Had Prolia from start of Lupron. Taking calcium since ending Lupron. DEXA done twice. Before RALP..."

@grandpun

One of the primary problems that Lupron causes is thinning of The bones. There was a doctor at one of the conferences about nine months ago, that specialize in bone health and said that everybody who is castrate resistant Should be on bone strengtheners. He emphasized that Lupron is really hard on the bones, And those were on it long-term should be on Strengtheners.

I forgot to mention that vitamin D is another one of the important things needed for keeping bones strong. That was another thing. My doctor mentioned I needed to take daily. I’m sure you’re doing that..

From AI

Lupron can cause bone loss (thinning of the bones) as a side effect, particularly with long-term use. This is because it can decrease sex hormones, which are important for bone density. Doctors can mitigate this risk by using "add-back" therapy with a progestin like norethindrone acetate, ensuring adequate calcium and vitamin D intake, and monitoring bone mineral density with DEXA scans.

@grandpun, you may wish to check out these related discussions:
- Did androgen deprivation therapy (ADT) cause bone loss for you?https://connect.mayoclinic.org/discussion/adt/
- Osteoporosis and Osteopenia treatment and prostate cancer?https://connect.mayoclinic.org/discussion/osteoporosis-and-osteopenia-treatment/
- Osteopenia Supplements that work? https://connect.mayoclinic.org/discussion/osteopenia-supplements-that-work/