Anyone have experience with Mirabegron for urinary urge incontinence?

I don’t even know what Mirabegron is so I can’t respond to your question. But I have struggled with incontinence all my life and am interested in the responses you get in this discussion.

So far, you are the only respondent - maybe because others read about the risks and decided against starting it.

Mirabegron is also called myrbetriq, harder for me to pronounce and remember.

I have avoided similar meds in the past due to their link with cognitive issues, but was told by my urogynecologist that there were no reports of Mirabegron causing cognitive issues.

I recently Googled this, however: "There have been post-marketing reports of confusion, hallucinations, insomnia and anxiety in patients taking mirabegron. The majority of these patients had pre-existing medical conditions or concomitant medications that may cause confusion, hallucinations, insomnia and anxiety." This causes me some anxiety.

I also have issues about my continuing need for acetaminophen (possible liver issues), increasing bp & many reports of hair loss with Mirabegron.

See more at:
https://www.drugs.com/comments/mirabegron/myrbetriq-for-urinary-incontinence.html#:~:text=Myrbetriq%20has%20an%20average%20rating,55%25%20reported%20a%20negative%20experience.
https://www.drugs.com/compare/myrbetriq

I have taken Myrbetric for ten weeks. It did nothing for my incontinence for 9 weeks then one night I stayed dry all night to my surprise. I have stayed dry ever since. I have had no side effects unless it could be hair loss. I had a difficult total hip replacement at the end of August and I attributed the hair loss to anesthesia. I spent ten days in the hospital post surgery. Now I read it could have been the Myrbetric. It is probably worth having thinner hair to not be incontinent to me. I found getting 90 days of pills by mail order pharmacy saved me $ 80 compared to the local pharmacy.

@ Queenie2030 - Thanks for the positive news.
Being dry all night for about a month sounds wonderful to me with my 10 yr. + nocturia (yawn . . . )
Pease keep us posted.

Good evening @notmoff, thank you for introducing a discussion about Mirbegron or Myrbetriq. I personally think this is a pretty amazing medication. After a sling surgery that was not successful, I was becoming more worried about how I was going to live with a constant lack of bladder control. My PCP wanted me to stop oxybutynin's negative impact on my cognitive decline.

Myrbetriq has been impressive. I can't remember when I last remained dry all night long. Halleluia! And I haven't noticed any mental confusion, insomnia, or greater anxiety since starting this medication.

This is still a nongeneric medication. From what I have read companies get 20 years before they have to share the ingredients for generic formats. It is rather spendy!

I would love to hear from anyone else who has had a positive response to Myrbetriq.

Chris

Very glad this topic came across my list of discussions. I’ve been on Oxybutynin for about a year to help with urgency and frequency. Bladder was “burned” due to radiation in the area following radical prostatectomy. Doesn’t seem to be consistently effective with those to issues, but my cognitive issues have increased. There may be other factors involved, but let’s get the possible Oxy side effect eliminated. Will review with my Urologist in a few weeks

Sadly after two weeks of staying dry the incontinence returned even though I have been on Myrbetric the entire time (since end of July). Now I only have problems at night some nights but not all. Not sure what makes the difference. Seeing urologist again on the 9th of November. Hoping for a better solution.

My AZ Mayo urology doctor took me off of Oxybutynin, which I’d been on for many years. I can’t remember what his exact reasoning was, but he felt that the medication was now doing more harm than good.

I was told oxybutin causes dementia or worsens it if you already have it. My urologist would not consider any drug except Myrbetric for that reason. It has helped my incontinence just not a complete control. Guess it makes a difference the cause of your incontinence.

Good morning @ldrlaw. That is exactly what my PCP said. I had been on Oxybutynin for several years. I posted above about my positive reactions to Myrbetriq. I was surprised that my Urologist had not heard of it or prescribed it. So my message today is to never bypass your PCP. What a great support she has been for 10 years. This is not the first time she has identified and proposed a medication change.

Her specialty is family care. She helps young kids prepare for school athletics and other activities. I sometimes think I am really one of her children.

I wonder how many other medications are also doing more harm than good as we learn more about our body's reactions.

Lately, I have read about OTC medications which have recently been found to still have
negative elements that were identified years ago. We all need to be our own advocates in many ways.

May you be safe, protected, and free of inner and outer harm.
Chris