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Success with low dose naltrexone for Autoimmune disorders

Posted by julie868 @julie868, Feb 13, 2020

Low Dose Naltrexone, otherwise known as LDN, seems to be helping a lot of people lately who have all different types of autoimmune disorders.
The information I read sounds very interesting and would like to know if anyone has tried it personally?

The theory that I read says that many autoimmune issues are caused by a deficiency in endorphins, endorphins regulate the immune system. LDN temporarily blocks the body's natural endorphin production for a few hours, this tricks the body into thinking it needs to increase endorphin production. When the blockade wears off, all the endorphins are released into the body, regulating the immune system and providing natural pain relief for the rest of the day. Apparently, LDN can increase your endorphins by up to 300%

LDNscience.org has a lot of information and research about it. You can also look at the writer, Annie Habler (@hablerannie) on Medium.com who wrote an article recently about the fascinating background and history of LDN.

Please let me know if you have tried it and what your experience was like. If you could let me know any details your condition,the dosage you used, any side effects, etc it would be helpful.

Thank you!

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

kennethreffeitt | @kennethreffeitt | Dec 13, 2023
In reply to @covidstinks2023 "My endocrinologist put me on Naltrexone because I was so sensitive to the other meds for..." + (show)
@covidstinks2023

My endocrinologist put me on Naltrexone because I was so sensitive to the other meds for Hashimotos (Hypothyroidism). It helped me greatly for about 3 months and also helped with my fibromyalgia pain. Then I started having peripheral neuropathy symptoms in my arms and legs and more migraines. My primary took me off of it since I am migraine prone and that was a side effect listed for Naltrexone, along with peripheral neuropathy as a side effect. I will have to also add, my B12 was low which can cause the peripheral neuropathy symptoms. I started B12 injections and quit the Naltrexone and the peripheral neuropathy symptoms went away. With that said, my symptoms may have been from low B12 & the Naltrexone both. I am 'ultra' senstive to medications. This may be a good fit for you. I would just recommend looking out for the 2 side effects I mentioned. I wish you the best. God Bless.

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My doctor tried four or five antidepressants and each one caused my intestines to feel like they were "quivering" all the time. Finally that Dr. left and the replacement, when hearing of same, turned to the Medical School student next to him and said: "ten percent of caucasians are such slow metabolizers that they need to halve their dosages and take them twice per day." It worked. I also have hypothyroidism and both the regular Rx and the Armour thyroid Rx cause everything in my intestines to change into watery extreme diarrhea.

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barbb22 | @barbb22 | Dec 14, 2023

I have taken LDN for at least 5 years and have noticed a decrease in chronic inflamation. My naturopath started me at 3mg then slowly increased the dose to 6mg. It was a slow and subtle change, but I do believe it is helping.

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cwitton1 | @cwitton1 | Jan 8 10:20am
In reply to @bandruid7 "Thank you Teresa. The greatest benefit I noticed was decreased fatigue, joint/muscle pain and severe bouts..." + (show)
@bandruid7

Thank you Teresa. The greatest benefit I noticed was decreased fatigue, joint/muscle pain and severe bouts of insomnia resolved. I felt less inflamed systemically and had much more energy.

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Are you still taking the LDN? How has it been from your post til now?

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cwitton1 | @cwitton1 | Jan 8 10:21am
In reply to @bandruid7 "I have not. Honestly, I've given up on allopathic medicine. They are great for trauma and..." + (show)
@bandruid7

I have not. Honestly, I've given up on allopathic medicine. They are great for trauma and serious infection but they have completely failed me for the last 7 years. They've done nothing but dismiss me & push pharmaceuticals that make things worse on to me. (And I'm a Mayo patient too!).
I'll stick to exercise, nutrition, nutriceuticals and myself to be my healer from now on.
It's funny, I've been in veterinary medicine for 30 years and 100% of the time we are able to diagnose even the most obscure diseases & disorders within two weeks. Our patients can't even talk!!!

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I feel you. I hope you’re doing ok.

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