Anyone else have Waldenström’s with a lot of bloating and pain around

I have Waldenström‘s macroglobulinemia and have been taking oral chemotherapy since last fall. I’ve slowly been having more trouble with going to the bathroom and now bloating, mostly in my abdomen, but also sharp pain and discomfort in my abdominal area as well as hands feet and my back is starting to hurt so badly that I can’t stand up straight. Recently found out that my spine is starting to have a lot of degeneration and wondered if anyone else is having anything similar to this happened to them.