1. < Autoimmune Diseases

antibody testing laboratory

Posted by 2catmom @2catmom, May 7, 2023

I’m looking for a US facility that will test for IgM antibodies to the phosphatidylserine-prothrombin complex (IgM aPS/PT.) Clinicians from Japan report this antibody correlates with cutaneous polyarteritis nodosa.
While it’s still off-label, testing for the IgG antibody to the same phosphatidylserine-prothrombin complex (IgM aPS/PT) is sometimes done when profiling antiphospholipid syndrome patients.

If you’ve been tested for antibodies to the phosphatidylserine-prothrombin complex, might you share the name of your testing lab?

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Mentor
John, Volunteer Mentor | @johnbishop | May 8, 2023

@2catmom, While we wait for others who may be able to share names of their specific testing labs in the U.S., I found a few that may be what you are looking for:

--- Mayo Clinic Laboratories - https://www.mayocliniclabs.com/test-catalog/Overview/64704
--- Labcorp - https://www.labcorp.com/tests/504439/antiphosphatidylserine-prothrombin-complex-igg

REPLY
2catmom | @2catmom | May 8, 2023

The support on Mayo Clinic Connect is wonderful!

Thanks @johnbishop for the Mayo Clinic and LabQuest links. From the CPT codes on those sites, I followed up on @kstar077 Quest suggestion and found Quest’s version https://testdirectory.questdiagnostics.com/test/test-detail/11447/phosphatidylserineprothrombin-pspt-antibodies-igg-igm?cc=MASTER

Amy

P.S. for those interested in the arguments for testing, here are some urls

open source
cPAN 2010 https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1346-8138.2009.00761.x
cPAN 2020 https://www.clinexprheumatol.org/article.asp?a=14687
APS 2014: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408156/pdf/cei0180-0218.pdf

paywall
APS 2019 https://www.sciencedirect.com/science/article/abs/pii/S0272271219300575

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