Antibiotic induced flare of PMR while on prednisone and MTX
I have been on prednisone for 13 months and was happily tapering down to 10 1/2 mg. Also injecting MTX weekly 40-50 ml. I developed a UTI and eye lid infection and asked for an antibiotic that would not affect prednisone’s ability to control the inflammation. I took Keflex for 3 days and then had a horrible flare of pain. Is there any antibiotic that doesn’t cause a flare? This is the second time this has happened to me and more infections are likely on prednisone. All the struggle to taper and now I am back up to 12 or 13 mg prednisone. Very discouraging. My send rate and CRP are still high in fact CRP has increased over the 13 months. As long as they are high should I avoid tapering? MTX injectable gives me GI effects like the pills did and I feel like I have the flu for 2 days after injecting. Any advice?