Anti-depressants to take in tandem with a low dosage of narcotic, for severe nerve pain.

Posted by Babyjoan @babyjoan, Aug 20, 2012

Anyone have a success story for taking Effexor (or similar drug) WITH a low dose of a schedule lll pain med, for degenerative disc disease neuropathy and a herniated disc?

Interested in more discussions like this? Go to the Neuropathy group.

There are different “classes” of antidepressants. Effexor is in the class of selective serotonin reuptake inhibitor. SSRIs are not very effective, if at all, for relieving neuropathic pain. The class that has demonstrated pain relief for neuropathic pain is TCA. Tricyclic antidepressants such as amitriptyline (Brand name is Elavil) are usually given in lower doses for this indication compared with their dose for treating depression. You may want to speak with your neurologist or pain management physician. You might have some other medical condition that would prohibit its use. I limited my response to your question regarding antidepressant use for your pain, but back pain is a complex issue involving multiple disciplines. I hope this helps you.


Friend on FENTYL patch that is changed every 3 days, she started with 25, after 6 months, up to 50. She also takes diazepam 5 mg every 4 hrs., but she used to be on every 6 until this worked better for the pain. She search for a medical massage, which has done wonders after she goes through a sauna and after massage, a jacuzzi once a week. For backup pain, doc gave her 2 mg of hydromorphone, but made sure she was emotional stable to handle the regiment and checks in with his nurse each week by phone and office, once a month. Each person has their own threshold for pain, injuries, coping, etc. she also goes to a local Chabad house to learn biblical meditation, as it helps the mind take control over the pain. So you might have to spend some time to find the right setup for yourself, and do not forget changing diet to help fight the pain.

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