Alternative treatment instead of Prolia injections

Posted by malliecallie @malliecallie, Feb 27 9:50am

Recently diagnosed with Osteoporosis, doctor prescribed Prolia injections. Because of possible serious side effects, I do not want to take it. I am 79, active, working as office administrator, walking an hour (fast walking) 7 days a week. I want to remain active and feeling good.

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@bec39

My mother is 90 and her PCP insists she needs to go on an osteoporosis drug, specifically Prolia, as her numbers are off the chart. She is terrified by what she has read about the side effects (as am I) and we’re trying to find her an alternative. She was on Fosamax for years followed by Forteo, but nothing since. I do agree she should be on something, though her Dr. says she can’t go back on another Bisphosphonate - is this true? I know she can’t go on Tymlos, Evenity is a possibility but only for one year. What about Raloxifene? I’ve never seen a conversation about that one. Any thoughts would be most helpful…

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bec39, talk to your mother's doctor about using Forteo again. My endo said since the black box warning was lifted on Forteo that some of her colleagues have started using Forteo again for their patients for a lifetime use of 4 yrs. As example, if your mother was on Forteo for two years prior, maybe she can use Forteo again. Check with her doctor. It's worth a conversation.

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@bec39

My mother is 90 and her PCP insists she needs to go on an osteoporosis drug, specifically Prolia, as her numbers are off the chart. She is terrified by what she has read about the side effects (as am I) and we’re trying to find her an alternative. She was on Fosamax for years followed by Forteo, but nothing since. I do agree she should be on something, though her Dr. says she can’t go back on another Bisphosphonate - is this true? I know she can’t go on Tymlos, Evenity is a possibility but only for one year. What about Raloxifene? I’ve never seen a conversation about that one. Any thoughts would be most helpful…

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Oh wow, I have not heard this. I will definitely check with her doctor, that would be the perfect alternative!
Thank you so much!❤️

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@bec39

My mother is 90 and her PCP insists she needs to go on an osteoporosis drug, specifically Prolia, as her numbers are off the chart. She is terrified by what she has read about the side effects (as am I) and we’re trying to find her an alternative. She was on Fosamax for years followed by Forteo, but nothing since. I do agree she should be on something, though her Dr. says she can’t go back on another Bisphosphonate - is this true? I know she can’t go on Tymlos, Evenity is a possibility but only for one year. What about Raloxifene? I’ve never seen a conversation about that one. Any thoughts would be most helpful…

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Hi @bec39 - I combined your discussion with an existing discussion titled "Alternative treatment instead of Prolia injections" - https://connect.mayoclinic.org/discussion/alternative-treatment-instead-of-prolia-injections to meet @gently and @malliecallie.

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I am 83. Still working and daily walks. I was diagnosed with osteoporosis about 14 months ago. I chose not to use drugs. I have been taking Bone Maximizer III 3 times a day and collagen once a day and just got my first scan. Spine went from -2.7 to -1.9. Left Hip from -2.6 to -2.3. No fractures or pain. Small change in right hip. Not sure why it is slower to respond. This is basically the program NASA uses

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@dwolf

I am 83. Still working and daily walks. I was diagnosed with osteoporosis about 14 months ago. I chose not to use drugs. I have been taking Bone Maximizer III 3 times a day and collagen once a day and just got my first scan. Spine went from -2.7 to -1.9. Left Hip from -2.6 to -2.3. No fractures or pain. Small change in right hip. Not sure why it is slower to respond. This is basically the program NASA uses

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@dwolf that is a lot of calcium in Bone Maximizer III! Microcrystalline Hydroxyapatite 4,000 mg contains calcium in addition to the 1,000mg calcium. Do you also get calcium in diet? And that is nowhere near enough D3. Has your D3 been tested? Sorry to express doubts: I am glad you are feeling good about it.

Your scores were not that bad before this treatment. As a person with fractures and much worse DEXA scores, I would be scared to try this. But you are in a place where you can afford to try and congrats on improvements.

But I hope you will check those calcium and D3 levels with your doctor!

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@windyshores

@dwolf that is a lot of calcium in Bone Maximizer III! Microcrystalline Hydroxyapatite 4,000 mg contains calcium in addition to the 1,000mg calcium. Do you also get calcium in diet? And that is nowhere near enough D3. Has your D3 been tested? Sorry to express doubts: I am glad you are feeling good about it.

Your scores were not that bad before this treatment. As a person with fractures and much worse DEXA scores, I would be scared to try this. But you are in a place where you can afford to try and congrats on improvements.

But I hope you will check those calcium and D3 levels with your doctor!

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You double counted the calcium.

"Calcium (from microcrystalline hydroxyapatite) 1000 mg 77%"

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@normahorn

You double counted the calcium.

"Calcium (from microcrystalline hydroxyapatite) 1000 mg 77%"

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I take additional D3 and have blood work to check levels of both D and calcium. My D was low before I started supplements. Calcium is good and I have veins checked annually. Thanks for the comment.

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@normahorn

You double counted the calcium.

"Calcium (from microcrystalline hydroxyapatite) 1000 mg 77%"

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@normahorn I didn't count it twice (see the bottom of the label) but I did make a mistake in what the composition of MCH is (it is 25% elemental calcium). Apologies. The important thing is that @dwolf's tested levels were fine. I was curious what the label means and what this supplement includes though. My mother took it for quite awhile.

The bottle label says https://femologist.com/products/bone-support#ingredients

Calcium (from microcrystalline hydroxyapatite) 1000 mg 77%

then below the line microcrystalline hydroxyapatite 4,000 mg

Here is info on dosing:
A typical dose of microcrystalline hydroxyapatite compound is eight 500 mg capsules; each capsule contains 125 mg elemental calcium, for a daily total of 1000 mg elemental calcium.

So the 4,000mg microcrystalline hydroxyapatite on the bottom of the label is actually 1,000 mg elemental calcium . But the calcium from microcrystalline hyroxyapatite higher up on the label says that 1,000 mg is 77% of the daily requirement, which is 924mg.

So the total for a daily dose of Bone Maximizer III would seem to be 1924mg calcium

I did think that microcrystalline hyroxypatite was just another form of calcium, but it seems the elemental calcium in it is 25% of the total mg. It still seems a little high but not as high as I first thought so again apologies!

I am curious about this supplement, since it has been mentioned in articles as helpful to us. It has other compounds besides calcium which are listed on the label. Thanks for introducing this!

Pub Med
"As an alternative to calcium, ossein hydroxyapatite compound is a complex protein mineral that has higher osteogenic effect when compared with mineral compounds or calcium supplement administered orally. Ossein hydroxyapatite provides benefits in the treatment and prevention of osteopenia and osteoporosis in women, including primary and secondary osteoporosis. Various studies suggest that ossein hydroxyapatite is more effective than calcium carbonate in reducing bone loss in postmenopausal women and in preventing bone loss as well."

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@windyshores

@normahorn I didn't count it twice (see the bottom of the label) but I did make a mistake in what the composition of MCH is (it is 25% elemental calcium). Apologies. The important thing is that @dwolf's tested levels were fine. I was curious what the label means and what this supplement includes though. My mother took it for quite awhile.

The bottle label says https://femologist.com/products/bone-support#ingredients

Calcium (from microcrystalline hydroxyapatite) 1000 mg 77%

then below the line microcrystalline hydroxyapatite 4,000 mg

Here is info on dosing:
A typical dose of microcrystalline hydroxyapatite compound is eight 500 mg capsules; each capsule contains 125 mg elemental calcium, for a daily total of 1000 mg elemental calcium.

So the 4,000mg microcrystalline hydroxyapatite on the bottom of the label is actually 1,000 mg elemental calcium . But the calcium from microcrystalline hyroxyapatite higher up on the label says that 1,000 mg is 77% of the daily requirement, which is 924mg.

So the total for a daily dose of Bone Maximizer III would seem to be 1924mg calcium

I did think that microcrystalline hyroxypatite was just another form of calcium, but it seems the elemental calcium in it is 25% of the total mg. It still seems a little high but not as high as I first thought so again apologies!

I am curious about this supplement, since it has been mentioned in articles as helpful to us. It has other compounds besides calcium which are listed on the label. Thanks for introducing this!

Pub Med
"As an alternative to calcium, ossein hydroxyapatite compound is a complex protein mineral that has higher osteogenic effect when compared with mineral compounds or calcium supplement administered orally. Ossein hydroxyapatite provides benefits in the treatment and prevention of osteopenia and osteoporosis in women, including primary and secondary osteoporosis. Various studies suggest that ossein hydroxyapatite is more effective than calcium carbonate in reducing bone loss in postmenopausal women and in preventing bone loss as well."

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Just want to add that I could be wrong on all of that so double check. I might be interested in that product so wanted to explore.

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@windyshores

@normahorn I didn't count it twice (see the bottom of the label) but I did make a mistake in what the composition of MCH is (it is 25% elemental calcium). Apologies. The important thing is that @dwolf's tested levels were fine. I was curious what the label means and what this supplement includes though. My mother took it for quite awhile.

The bottle label says https://femologist.com/products/bone-support#ingredients

Calcium (from microcrystalline hydroxyapatite) 1000 mg 77%

then below the line microcrystalline hydroxyapatite 4,000 mg

Here is info on dosing:
A typical dose of microcrystalline hydroxyapatite compound is eight 500 mg capsules; each capsule contains 125 mg elemental calcium, for a daily total of 1000 mg elemental calcium.

So the 4,000mg microcrystalline hydroxyapatite on the bottom of the label is actually 1,000 mg elemental calcium . But the calcium from microcrystalline hyroxyapatite higher up on the label says that 1,000 mg is 77% of the daily requirement, which is 924mg.

So the total for a daily dose of Bone Maximizer III would seem to be 1924mg calcium

I did think that microcrystalline hyroxypatite was just another form of calcium, but it seems the elemental calcium in it is 25% of the total mg. It still seems a little high but not as high as I first thought so again apologies!

I am curious about this supplement, since it has been mentioned in articles as helpful to us. It has other compounds besides calcium which are listed on the label. Thanks for introducing this!

Pub Med
"As an alternative to calcium, ossein hydroxyapatite compound is a complex protein mineral that has higher osteogenic effect when compared with mineral compounds or calcium supplement administered orally. Ossein hydroxyapatite provides benefits in the treatment and prevention of osteopenia and osteoporosis in women, including primary and secondary osteoporosis. Various studies suggest that ossein hydroxyapatite is more effective than calcium carbonate in reducing bone loss in postmenopausal women and in preventing bone loss as well."

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Hi windyshores,

There isn't a separate 924mg of Calcium. The 77% is referring to the 1000mg which comes from the 4000mg Calcium Hydroxyapatite. The company (like Doctor's Best) uses 1300 as 100% RDA for calcium

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