Taking Eliquis and Metoprolol for A-fib: Concerned about side effects

Posted by damari @damari, May 25, 2020

Just diagnosed. Doctor prescribed Eliquis and Metoprolol. I was wondering what side effects common. I read there is a rare side effect of hair thinning for metoprolol. (take 25 mg 2x day) Also read that Eliquis can sometimes cause some stomach discomfort. (5 mg 2x day) Can either medications be taken in lesser amounts?

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I'm 81yo. Have Tachycardia and occasional AFIB. Taking Metoprolol 25mg 1xday and baby aspirin, that's all. Metoprolol works for me. No side effects. I now feel free to do strenuous hiking and occasional jogging w/o any side effects and rarely any palpitations.


this is on Metoprolol

Serious side effects of Metoprolol
Along with its needed effects, metoprolol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking metoprolol:

More common
Blurred vision
chest pain or discomfort
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
slow or irregular heartbeat
unusual tiredness or weakness


The most common adverse events were related to bleeding. Common adverse reactions were anemia, hemorrhage, and nausea.[Ref]

Patients with diabetes had more bleeding events than non-diabetic subjects. Hemorrhage includes hematoma, and vaginal and urethral hemorrhage. Postprocedural hemorrhage includes postprocedural hematoma, wound hemorrhage, vessel puncture site hematoma, and catheter site hemorrhage.[Ref]

Very common (10% or more): Minor bleed (11.7%)

Common (1% to 10%): Anemia postoperative, clinically relevant nonmajor bleed, hemoglobin decreased, anemia, hemorrhage

Uncommon (0.1% to 1%): Postprocedural hemorrhage, hemoglobin decrease of 2 g/dL or more, transfusion of 2 units or more red blood cells, fatal bleed, thrombocytopenia, hemorrhagic anemia


What I have typically done if prescribed any medications, is to do a search on what the side effects are. Eliquis appears to have quite a few; however, we also need to recognize that the drug companies are obligated to list any and all side effects. All drugs have side effects. I guess the question you need to ask is, are the side effects worse than the condition the drug is trying to remedy. I don't like the idea of drugs personally because I believe that in most cases, they start a person on the treadmill of taking drug after drug to alleviate side effects. I speak from experience here. I never used to question what my doctor prescribed until I got up to the point of 5 drugs. I began a major research project at that point and realized that doctors are taught how to treat symptoms and not causes. I prefer to find out what the underlying cause of my illness is. If drugs are needed to start me on the right path, I can accept that; however, I do my homework.


New to Afib on Xarelto and 81 aspirin - 83 yrs old and also have a stint in main artery was 75% blockage. Does anyone know if Xarelto or eliquis better? Also note most on these drugs also on Metropolis? Any knowledge on these drugs appreciate.

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I take them both Eliquis for about 3-4 years the other seems like forever. Only issue are that I frequently feel a bit "woosy" with the first dose of Eliquis in the AM -- may be like that for about an hour. Otherwise nothing to note. However, I would venture to say with Rx it seems very evident that different Rx affect different people differently.


Be careful. I ended up with 15 listed side effects of Eliquis. Both Eliquis and Metropolol cause hair loss. I had The Amulet implanted two months ago and no longer take blood thinners and never will again as I have long-lasting side effects.

I never understood why doctors wanted my blood to clot faster anyway. It seems counterintuitive.


I have just been diagnosed with occlusion of the fibular arteries on both of my legs.
It started with a frozen feeling in my feet, which are often cold.
In neuologist confirmed it is not norapathy.
So a CT scan was done with injection of iodine to a video this condition..
I have been referred to a cardiologist, but they have not yet called me.
Can anyone clarify what happens from this point on?
Thanks! Vivianne

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Hi, vivianne777. My experience was similar. Concerned that I might have developed blood clots in my legs causing occlusions there, my PCP prescribed ultrasound imaging which found no clots! Looking into my abdomen, my gastroenterologist prescribed a CT Scan which yielded a detailed report by a radiologist who was most revealing. I hope that whoever ordered your CT Scan gave you a copy of the report, which would have been a primary basis for you and your physician to decide on a treatment plan. Martin


Hi, @timely. I can recommend two articles giving a lot of information about Carvedilol.

One is from the company that makes it: https://www.COREG.com.

The other is from the FDA: https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020297s020pi.pdf.

Let us know if they helped prepare you for discussions with your Internist and your Cardiologist. Martin



Please mention your side effects with Carvedidol.

My new cardiologist is switching me from Cartia to Carvwdidol.

I take Eliquis also.
I am afraid to take this new med.
One of the side effects is you should not take it if you have Raynauds.
I will run this by my Internist next week.
I am also concerned about the other side effects.

Would appreciate any thoughts that you have.

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I have Raynauds…

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