ADT and rising PSA

Posted by mjp0512 @mjp0512, May 20 8:27pm

I could have added this to my previous discussions of “PSA Wrong Direction” but felt this is important enough for its own thread.

A couple of things I’ve learned since I started that first discussion in December:

1. If you are on ADT, your PSA is NOT SUPPOSED TO RISE!

If your PSA starts going in the wrong direction, even if it is a minimal increase, as mine was, DO NOT listen to the conventional wisdom of…

“It’s probably just a “minor bounce” or “lab variance” or “inflammation from radiation”. We’ll check it again in a few months”.

If you are on ADT, your PSA is NOT SUPPOSED TO RISE!

INSIST on monthly PSA testing immediately. Had I done so last December, the flare up on my spine would have been caught sooner, treated sooner, and I might still be able to walk normally and sleep through the night. Instead, it’s six months later and I don’t even start treatment until next week. It’s a $60 test. DEMAND it. If it turns out to be nothing, no harm, no foul. But if you can catch something earlier, maybe it can be treated before it hurts.
PSA:
4/21/25 - 30.11
6/7/25 - start ADT
7/9/25 - 0.55
8/26/25 - 0.19
10/2025 - IMRT
12/3/25 - 0.23
3/17/26 - 8.80
4/1/26 - 10.29
5/18/26 – 14.90

And…

2. Prostatic Adenocarcinoma is a very slow growing cancer…until it isn’t.

That is all…Don’t make my mistake.
Enjoy your day!

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for mjp0512 @mjp0512

@jeffmarc - Very surprising appointment with my DDS today. He is very familiar with Xgeva and wholeheartedly recommends that I take it. I asked the question, "If you had my mouth, would you take it?"

His reply, "Without a doubt, especially if I had your spinal metastases to go along with your mouth. It is working wonders on bone mets, especially vertebral. I'll gladly sign a release if you need one."

Looks like the decision is back to me.

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@mjp0512
Xgeva is real good, Zometa Has a lower chance of osteonecrosis. You could ask your doctor about it.

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Profile picture for Jeff Marchi @jeffmarc

@mjp0512
Xgeva is real good, Zometa Has a lower chance of osteonecrosis. You could ask your doctor about it.

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@jeffmarc - I'll do that. Thanks!

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