1. < Prostate Cancer
Profile picture for ira527

60 yr old psa increased from 2 to 3.97 in 1 yr, what should i request

Posted by ira527 @ira527, Sep 7, 2025

very concerned, i want to be very informed please share TY

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Profile picture for jime51
jime51 | @jime51 | Sep 9, 2025

Mine went from 2.8 to 4.4 in a year but PCP wanted to wait. Next year, 5.5 and off to urologist. I missed by a year. Digital exam twice found nothing; MRI was unclear. Biopsy confirmed lesions in prostate, PSMA PET scan found metastases to lymph nodes. Don’t wait. As others commented, the jump up in PSA is the trigger for testing.

REPLY
Profile picture for animate
animate | @animate | Sep 9, 2025

Similar story here. My PSA jumped from 2.53 to 3.90 in 1 year. Urologist ordered an MRI, which resulted in a PI RADS lesion of 4. I then got a Biopsy, which resulted in 5 sampled cores with Gleasons 6, 7 and 8.

Just last week I got my PET-PSMA scan, which fortunately shows no expansion outside the prostate capsule.

I am now scheduled for RALP in a few weeks from now.

Don't wait, go to your urologist and go through all the required tests to find out what's going on, to get treatment right away, if required.

REPLY
Profile picture for timoppermann
timoppermann | @timoppermann | Sep 9, 2025

Sorry I was saying psa 120 not 1.2 and 238 and not 2.38 mri report looks like has gone into nurovascular bundle with bulging in bladder

REPLY
Profile picture for timoppermann
timoppermann | @timoppermann | Sep 9, 2025
In reply to @jeffmarc "Why aren’t they doing a PSMA pet scan. That has replaced the bone scan and the..." + (show)
Profile picture for Jeff Marchi @jeffmarc

Why aren’t they doing a PSMA pet scan. That has replaced the bone scan and the CT scan. As long as your PSA is above .5 or so the PSMA PET scan will show Metastasis in many more places than the CT scan will.

Have you gone to a center of excellence to get a second opinion? It’s pretty clear that the place you are getting treatment may not take your best interest into account. Are you working with a Genito Urinary Oncologist, The ones who specialize in prostate cancer, not a medical oncologist who works with all different types of cancer and doesn’t specialize and keep up with the latest technology.

Of course, if you live in Canada, you may not have a choice.

Jump to this post

No just urologist.

REPLY
Profile picture for timoppermann
timoppermann | @timoppermann | Sep 9, 2025

Im an retired nurse and I know that psa should be well below 10 not in hundreds like mine i just trying to grasp all bad reports getting

REPLY
Profile picture for timoppermann
timoppermann | @timoppermann | Sep 9, 2025

Thank you everyone I appreciate input very much

REPLY
Profile picture for timoppermann
timoppermann | @timoppermann | Sep 9, 2025

The first question out of my urologist mouth was why didn't you come to me months ago instead of letting psa be sky high..

REPLY
Profile picture for steveapplebaugh
steveapplebaugh | @steveapplebaugh | Sep 9, 2025
In reply to @retireditguy "I agree with the other commentors about finding a urologist and getting a PSE test before..." + (show)
Profile picture for retireditguy @retireditguy

I agree with the other commentors about finding a urologist and getting a PSE test before a biopsy. When in early 2024 I had a rising PSA that went from 2.8 to 4.25 over about 15 months, my urologist followed a pretty convential path and ordered another PSA test and an MRI (3T) with contrast. The MRI was a piece of cake, but then I'm not claustrophobic. The MRI tech gave me an IV, and then I lay in the MRI for about 20 minutes with a set of headphones playing music. The hardest part was just trying to lay still. The MRI showed a lesion and the radiologist report (which I got at the portal of the lab which did my MRI) said it was PI-RADS 4 (high risk of cancer). Interestingly the follow up PSA had come down to 3.24. I got a 2nd reading of the MRI results and the 2nd radiologist also gave me a PI-RADS 4 so I went ahead and got a fusion biopsy (which gives high confidence they biopsy the actual lesion). The biopsy found plenty of cancer, so the last drop in the psa was a false signal. I guess my point is while there are various ways to proceed, just be sure to follow up on it. It might well be nothing, but if it is prostrate cancer you'll have many more options finding it early as compared to late. BTW, I'm not a medical professional but just a layman, so take my comments with a grain of salt. Best wishes.

Jump to this post

I completely agree with you, retiredguy. My personal narrative mirrors yours very closely. I had my MRI fusion intrarectal biopsy this morning. Both procedures (MRI and biopsy) were easy, then again, I am not queasy or claustrophobic. Besides, my urologist is amazing, and I respect and trust him. The radiologist explained that he could not discern if the sole lesion was PI-RADS 3 or 4; my urologist said that he would call it a PI-RADS 3. Now, I wait for the pathology report -- and go from there. Stay strong, everyone!

REPLY
View MoreView Less
Please sign in or register to post a reply.