1. < Prostate Cancer

Anyone had a decipher test done? Did the results impact treatment?

Posted by rkurtzjr @rkurtzjr, Jan 1 1:49pm

I understand it may help with adt decision

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rkurtzjr | @rkurtzjr | Jan 2 3:52pm
In reply to @seasuite "@rkurtzjr SBRT in my case was a 'boost' therapy at UCSF involving treatment sessions 950 cGy..." + (show)
@seasuite

@rkurtzjr SBRT in my case was a 'boost' therapy at UCSF involving treatment sessions 950 cGy x 2 only. I'm not sure if they updated the mapping, but, doubt that given the small number of fractions. Cyberknife treatments preceded VMAT EBRT 180 cGy x 25 at Stanford. I chose Cyberknife over HDR brachytherapy done by Dr. Roach, who published a report comparing efficacy, since it was far less invasive, among other reasons.

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Thx. Not sure i completely understand your treatment sequence. Can you expand and explain the setting for your choices? Thx

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1 reply
toolbelt | @toolbelt | Jan 2 4:21pm
In reply to @heavyphil "Does anyone know if the Decipher Test can be done with blood only? Had prostate removed..." + (show)
@heavyphil

Does anyone know if the Decipher Test can be done with blood only? Had prostate removed almost 5 yrs ago and no genetic testing was done. Had Gleason 4+3 on practically entire right lobe; left and median totally normal. PSA has been rising and is now .15....next PSA test in a week at Sloan Kettering. If it hits .2 they are scheduling PSMA scan but I am more concerned with the duration of hormone treatment which would also be necessary. Don't mind 6 months but don't think I can hack 12-18 months....ugh!! Many thanks in advance! AL

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The Decipher is run on prostate biopsy cores or on the tumor material if you have a prostatectomy.

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jasonfarmer | @jasonfarmer | Jan 2 6:54pm

I had decided on surgery and after having decipher test showing I was at 93% (highly aggressive) it just confirmed decision to do surgery. So yes I feel decipher test is worth doing from my point of view.

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heavyphil | @heavyphil | Jan 2 9:15pm
In reply to @toolbelt "The Decipher is run on prostate biopsy cores or on the tumor material if you have..." + (show)
@toolbelt

The Decipher is run on prostate biopsy cores or on the tumor material if you have a prostatectomy.

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THANKS, buddy, thought so. So no other tests available at this point to aid in treatment as far as hormones are concerned? Thanks again!

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jc76 | @jc76 | Jan 3 8:08am

@rkurtzjr
Decipher test should become standard. It does not require any further biopsies it uses the biopsies already taken. It is expensive though but if your insurance does not cover it they will bill you based on your income. Medicare does cover it.

I had it done with a risk level on intermediate from Gleason score. The Decipher came back low risk. This changed my treatment plan from radiation with hormone treatment to radiation without hormone treatment needed based on oncologist/radiologist at Mayo Jacksonville.

Some other test you should consider are the PSMA and bone scans. This can also further determine the level of your cancer and if within your prostrate or has spread.
Good luck

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seasuite | @seasuite | Jan 3 8:46am
In reply to @rkurtzjr "Thx. Not sure i completely understand your treatment sequence. Can you expand and explain the setting..." + (show)
@rkurtzjr

Thx. Not sure i completely understand your treatment sequence. Can you expand and explain the setting for your choices? Thx

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This thread provides a bit more context: https://connect.mayoclinic.org/discussion/transperineal-biopsy-options/?pg=2#comment-970630

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