I am commenting for my husband who suffered extreme side effects from taking Eliquis but was required to stay on the drug until he could have the Watchman Implant (left ventricle appendage closure). Once he passed through the 6 week period of healing with the Watchman, we removed him from the blood thinners and he began to improve.

With intensive physical therapy and a combined GABA supplement (200 mg), CBD oil (250 mg), and micro-dose of hemp THC (0.56 mg), his neuralgia came to an end and he is upright and happy again after 7 years of chronic pain and debilitating psycho-motor dysfunction.

The side effects were dominant in the lower appendages (distal) with spasms and continual tightening of the muscles. His knees and elbows contracted, toes pointed outward, and he had hallmark symptoms of what might be described as Stiff Man Syndrome. Wheelchairs, motor scooters, canes, and walkers were all a part of his maintenance. He lacked bowel and bladder control. Sleeping was a nightmare for him.

Now he is returning to good health once more.

From literature, it appears that Eliquis converts Prothrombin blood clotting protein from the liver into Thrombin (an anticoagulant), which is a positively charged molecule. Excess positive charges on GABAergic receptors may lead to over-excitability of nerves.

Please do not disregard the complaints folks have about side effects. We were fortunate that our doctors listened to our concerns and acted accordingly!