Anyone had AC-T chemo combination for breast cancer?

Posted by dmosssadler @dmosssadler, Nov 7, 2023

Good afternoon,
Wanted to ask..has anyone undergone chemotherapy with all 3 chemo drugs/ medications called "ACT"?

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@auntieoakley

I saw this thread pop up and remembered you had your first chemo a few days ago.
How are you doing after treatment #1?

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Treatment 1 infused well but I had to take Olanzapine for 1st 4 days along with 2 more anti-nausea meds & the meds had me soooo Zombied out & I was feeling shaky...so I stopped taking all 3 anti-nausea meds & I started better..but ti took about 4 days to get back to myself.
So...Chemo #2 is this coming Wednesday..

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@katgob

From my experience, these choices are based on your diagnosis. For me, I was only to get the "Red Devil" every 3 weeks. But, I had my genetic test back, which gave me two others. I had Brca2 and received Carboplatin and Taxol. I got the Adriamycin (Red devil), only one dose following my 12 weeks of the other two. I had a blood reaction called Pancytopenia and did not get the final 3.
I had DCIS, Stage 2 with Brca2. At Surgery time it was noted no lymph node involvement in the 3 sentinels.
It seems your 3 might be the protocol for the lymph node involvement.
You will get more responses, but this is mine.
Keep us posted.

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I did experience the Red Devil & my urine was red...but now it has tapered off...but this coming Wednesday I will have my 2nd infusion...so now I know to expect red urine.

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@dlmdinia

I had all three chemo drugs you listed. Red Devil is nicknamed that as it is blood red, and your urine after each treatment will be red for a day or two. It is also so toxic that there is a maximum lifetime dosage. You'll probably be told to hydrate well to flush it from your system asap. I always took a large water bottle with me to drink during treatments and drank a minimum of 10 glasses of water per day Ask your infusion nurses what to expect and what you need to do or take to prevent or alleviate side effects. I had anti-nausea meds that worked great. I had a lumpectomy, chemo (16 infusions) and radiation. I was stage three and had lymph node involvement. I'm 3 years out and currently taking Letrozole to prevent it returning.

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Yes the nurse said to flush twice& the close the lid before I flushed the toilet & I also use Lysol Wipes each time I use the toilet.

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@slrny2000

I had this treatment in 2014 for the same diagnosis. I had a port placed in my chest for the infusions. 4 infusions of the AC (#1&2 combined) done every 2 weeks, and then weekly for 12 infusions of the Taxol. I believe it is the "standard" of treatment for this particular kind of breast cancer. AC is called the red devil because it is red in color and it can be unkind to your hair. This is the one that more than likely will cause hair loss. Mine started a few days after the 2nd dose. You'll probably have labs drawn before starting treatment as well as possibly an EKG. I would highly recommend asking for the medication EMEND, it is an antiemetic to help prevent nausea. I am sorry if I am giving too much information, it's the nurse in me. . . . I wish you the very best and please ASK, ASK, ASK questions of your treatment team, don't be intimidated, it's your body, your life.

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I want to thank you for sharing your journey with me....they gave me 3 anti-nausea meds to help if I get nauseous...
I didn't get nauseated too much cause I took all 3 meds....it was the exhaustion that had me

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@katgob

It is odd that Adriamycin. I heard of it as Red Devil and as has been said, I was told my pee would be red/orange. It was on that the day I got home and the day after. For me, I had what is called pancytopenia. I only had one dose of the Red Devil, as i was hospitalized due to severely low blood counts. I had heard it was the toughest chemo. WE ARE ALL DIFFERENT!! I had 12 rounds of the other two. One set a week. Cumulative doses were too much. I was stage 2. No lymph nodes. I went on "parib" pills, but the 1st one did the same thing to my blood. Surgery was to be scheduled in 3 weeks. I got Covid!! One more month. Surgery.

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Thank you for sharing your journey with me!

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@seathink

I had that combo -- 8 rounds of A/C every other week and then 12 weeks of the Taxol.

For me the worst side effect was the constipation, I would recommend doing *everything* you can to prevent it.

Another thing I regret, for my A/C they had me chew ice to prevent mouth sores and I hate chewing ice, so when they told me to ice my hands and feet during Taxol to prevent nueropthy I didn't and I got it in my toes on the last treatment. 🙁

Good luck!

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Thanks for sharing your journey with me & I did hear about ice water for hands..I will try this for my #2 infusion.

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@auntieoakley

Original diagnosis of invasive breast cancer not DCIS, but I took these drugs.
They called it TAC, presumably because they gave all three at once. It was a very hard regimen of drugs, I was lucky to have the support I had at home.
My best advice is make sure you have plenty of nausea medicine, and rest when you need to. You will likely have good and bad days, but it won’t last forever. I just counted them down on the bad days and celebrated the good days.
You said end of November which reminded me that I started in December, 20 years ago. It was certainly a different time for oncology patients. Are you due to start soon? All the drugs at once or separated like some of the comments above?

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Thanks for sharing your journey with me.

I had my 1st Chemo week before last.. I am scheduled to have #2 infusion next Wednesday....
So I go every other week & it will be for 8 rounds.

Then Radiation.

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@dlmdinia

You should not be fasting during chemo. That is against every protocol I've read. There are very effective drugs for nausea. Take the advice of your oncologist or your infusion nurses. I had 16 infusion treatments with these drugs and never once had more than mild queasiness that dissipated with the meds. Best advice? Talk to your infusion nurses. They have a wealth of knowledge and advice ready to be tapped.

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When I had my 1st infusion...the nurse asked if I wanted lunch..I wasn't hungry..so I said..No I didn't want any lunch & the nutrionst was in my cubicle & said to me...You need to eat especially about to recieve chemo & you don't want to take those harsh drugs on an empty stomach....
So I told the nurse...Yes...please vring.me lunch..it was good that nutrionist was there...
So my lunch consisted of a Tuna Sandwich, a fruit cup; Lorna Doorne cookies; bag of chips; cranberry juice & apple juice!
I enjoyed it, needless to say!

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@dmosssadler

Thanks for sharing your journey with me.

I had my 1st Chemo week before last.. I am scheduled to have #2 infusion next Wednesday....
So I go every other week & it will be for 8 rounds.

Then Radiation.

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How are feeling after your first treatment? Once I got started, my anxiety dropped fast, then it was just getting it done.
You can try alternating your anti nausea meds as they all kind of work a little differently. Take whatever you need to get through the worst days and don’t forget to drink and get that chemo flushed back out.
Did they give you odansetron/zofran? That one made hubby less sleepy than some of the others.

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@dmosssadler

I want to thank you for sharing your journey with me....they gave me 3 anti-nausea meds to help if I get nauseous...
I didn't get nauseated too much cause I took all 3 meds....it was the exhaustion that had me

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You're welcome! If what I've experienced can help even one person then it's worth sharing!! Glad you were given the medications. yes, the exhaustion is real and you really need to rest.

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