Hi @ducklynn, it can be scary to learn that you have factor V Leiden. As you live with knowing you have this, hopefully you will become less fearful of injury. You might appreciate this related discussion:
- Factor V Leiden: What exercise helps with blood clots? What to avoid?
https://connect.mayoclinic.org/discussion/factor-v-leiden/
I'm also tagging fellow members like @dhutch @maribel8 @emarcatkin @sps488 who have experience with factor V Leiden and Eliquis, although I don't know if they experience headaches.

Did your headaches only start with the medication or since you had the virus last week? Have they subsided?