@covidstinks2023
I have the same issue as you. I had told my doctors for years about all my ADRs to a variety of meds and how pain meds not only caused ADRs for me, but they didn't help my pain one bit. Most doctors just blew off what I was saying and kept prescribing the same meds. When I did some genetic testing and the list of key enzymes needed to metabolize most drugs came back and most of mine were abnormal, especially the ones that were flagged as "poor metabolizer," I felt so validated. Poor metabolizer means drugs linger in your system and become toxic in addition to being ineffective. Suddenly, it all made sense. Unfortunately, not all doctors buy into pharmacogenetics even though I have a list of major ADRs with so many meds. I try to look at the metabolic pathway for each new drug prescribed and go from there. I'm not sure how much it has helped me. I mostly just avoid new meds out of fear. The day the pharmacies and/or doctors can load our genetic information into their database and use AI to flag drug issues and dosage adjustments, that will be great.

By the way, I was also the child with all the health issues in my family. However, my two very healthy brothers both died young from their cancers and I'm still here. They both had cancers that are typically diagnosed too late, but I also feel like having so many health issues had me going to doctors and having scans often enough to catch my cancers earlier. My aunt was the sickly one of four siblings and she is also the soul survivor in her birth family. So there's the silver lining to having an array of health issues, at least for me and my aunt. My best to you as well.

Which testing did you do? My testing was done through color.com as an add on with genetic cancer testing.