Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)

Posted by richyrich @richyrich, Nov 2, 2016

I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you

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Thank you for your kind words.

Please know that I do not have “amazing inner strength”. I have done horrible things to those I love and for years wanted to escape my consciousness by killing myself.

I’m just an average sixty year old white guy who was and is desperate enough to ask questions.

Venlafaxine and other psych meds do not alter the brain slightly the effect of these medications go beyond anything that science fully understands. This is not my opinion it is the state of the current science.

The information was always there I just never bothered to check.

Further the science is clear that the effects are not confined to the brain but are throughout the patients body. Whoever thought science could mess with the brain, the organ that controls everything, and not affect the body makes Victor Frankenstein look sane.

Providers; beware hubris!

There may not be anything at all wrong with your brain, at least not before venlafaxine.

The science is now also pretty clear that much of what we call mental illness would be better described as metabolic illness.

I try not to tell people what to do but I will make an exception; anyone suffering from mental illness should read “Brain Energy” by Dr. Palmer. He is the head of psychiatry at McLean/Mass General and a professor at Harvard. In short, kind of the top of the pile in mental healthcare.

This book saved my life. I was about to blow my head off with a shotgun when I decided to mow the lawn instead, go figure.

I had downloaded this book to listen to one day.

My journey to wellness began that day.

If you have time you can review my post and see how unlikely of a candidate I was to make it to the next day let alone have a life of peace and joy.

My parole officer commented at our last meeting, that she never new if I would live to the next months meeting.

I hope you find the peace you deserve.

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Profile picture for dfb @dfb

Thank you for your kind words.

Please know that I do not have “amazing inner strength”. I have done horrible things to those I love and for years wanted to escape my consciousness by killing myself.

I’m just an average sixty year old white guy who was and is desperate enough to ask questions.

Venlafaxine and other psych meds do not alter the brain slightly the effect of these medications go beyond anything that science fully understands. This is not my opinion it is the state of the current science.

The information was always there I just never bothered to check.

Further the science is clear that the effects are not confined to the brain but are throughout the patients body. Whoever thought science could mess with the brain, the organ that controls everything, and not affect the body makes Victor Frankenstein look sane.

Providers; beware hubris!

There may not be anything at all wrong with your brain, at least not before venlafaxine.

The science is now also pretty clear that much of what we call mental illness would be better described as metabolic illness.

I try not to tell people what to do but I will make an exception; anyone suffering from mental illness should read “Brain Energy” by Dr. Palmer. He is the head of psychiatry at McLean/Mass General and a professor at Harvard. In short, kind of the top of the pile in mental healthcare.

This book saved my life. I was about to blow my head off with a shotgun when I decided to mow the lawn instead, go figure.

I had downloaded this book to listen to one day.

My journey to wellness began that day.

If you have time you can review my post and see how unlikely of a candidate I was to make it to the next day let alone have a life of peace and joy.

My parole officer commented at our last meeting, that she never new if I would live to the next months meeting.

I hope you find the peace you deserve.

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I'll order the book today! I read a book recently about using your mind to change the neural pathways in your brain. The idea is that certain "negative" reactions become the paths of least resistance. Say something bad happens like I forget an appointment. This triggers a ridiculous reaction in my head where I feel I'm just so stupid and worthless and never get anything right which is silly. But the mental anguish once started is the same as if it were justified and I can't get out of it. If I immediately step back, realize that forgetting is something everyone does, it just happens, I can stop to some degree the avalanche of negative feelings. The idea is that the negative neuronal pathway is also the path of least resistance; it's a reaction that has gotten to the point where it's become hardwired. The book I read posited that with conscious effort, mind over brain, one can gradually activate other, more positive reactions, literally rewire the brain connections to produce a more "sane" outcome. I'd give you the tile but I leant the book to my son-in-law who has a touch of OCD and was fascinated by the concept. I"ll be over there today and will get the title/author from him.

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I have also spent many years degrading myself with words and deeds.

I believe our biology accommodates our environment. If I speak harshly to myself my Brian and Body take it personally.

I try very hard not to do that anymore.

When I do speak harshly to myself I try to remember to apologize just as I would to anyone else.

Be well.

I hope you find peace.

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We speak thoughts into reality.

The bad news is, we can create a world of misery for ourselves by being merciless towards others and ourselves.

The good news is, we can turn that around. Words of compassion, forgiveness, and gratitude make the world around us better. Don't believe me? Try it.

Forgiveness starts at home. Be brave -- do something radical and unexpected -- forgive yourself.

The time is now.

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Profile picture for malo @malo

This may sound stupid but why do you (and others) want to quit? Is there a side effect or health risk I don't know about? I've been taking Effexor for over 20 years and my doctor has never mentioned quitting. When I forget or am late with a dose I notice that a feeling of dread comes over me. When I make small, essentially irrelevant mistakes my self image immediately goes to the "I'm stupid, hopeless, worthless; why can't I deal with life. What's wrong with me? place. If I lose say 10 years of my life due to this drug I'd truly consider it a fair trade.

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I came back here to ask this same question. Reading response.
Thank you

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Profile picture for chicago1211 @chicago1211

I was taking 150mg of Ven for a year then 225mg for another year. Since they stopped helping me at all and my depression was there again, I questioned myself why I take them and discontinued taking them. I’m going through hell right now I want to kill my self but at least there’s no such miserable feeling anymore that I’m hooked on useless medication. Well, seems like my body was hooked. There’s no way out apparently. I don’t want to take that poison anymore even though my cells are craving for it. My mind knows it’ll just bring me back in the vicious circle.

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How are you doing??

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Profile picture for intendtorecover @intendtorecover

I took Effexor for ten years. It has taken two years for me to rebound.
I used a combination of talk therapy with accupuncture. I also take herbal supplements and vitamins. Additionally, removing as much sugar and processed food from the diet can help tremendously.
I went through a little personal hell, while withdrawing this horrible drug. I lost 50 pounds, has horrible sleep disturbances, developed anxiety and depression. I originally started using it for the pain associated with fibromyalgia.
Today I'm living a mostly anxiety and depression free life.

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Two years?? I cannot wake up with this anxiety for the next two years. 3 months so far and I can't take it.

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Profile picture for susanh824 @susanh824

Hi, I’ve seen lots of posts mentioning having withdrawal, but few mention what the symptoms are. I have started to withdraw. Started at 225 mg, but have cut out one 75 mg pill every third day. Around this time, I started experiencing waking up in the middle of the night and not being able to fall back asleep. I’ve always had problems falling asleep, and take Ambien, Magnesium and Tizanidine to help. But once I was asleep, I slept through the night. Not any more! This seems like a sudden change, and I can’t think of anything else that would have caused it.

Has anyone else had this symptom?

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Oh dear, this is WAY too fast. You will feel worse, much worse. I would reinstate ASAP to 200mg.

I dropped by 12.5mg every 3 weeks, and 2 months after 0mg my horrible withdrawal started. I was originally on 112.mg

You need to taper by 10% every month but stabilize yourself first and do it longer if you have to. It gets harder after you hit a smaller dose. Then there is the 'endgame' when you reach like 5mg.

How are you now in December??

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Profile picture for justynan @justynan

Oh dear, this is WAY too fast. You will feel worse, much worse. I would reinstate ASAP to 200mg.

I dropped by 12.5mg every 3 weeks, and 2 months after 0mg my horrible withdrawal started. I was originally on 112.mg

You need to taper by 10% every month but stabilize yourself first and do it longer if you have to. It gets harder after you hit a smaller dose. Then there is the 'endgame' when you reach like 5mg.

How are you now in December??

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Thanks for the advice! Honestly, I gave up and returned to 225 mg when the withdrawal symptoms became too much for me. I’ll probably wait until the holidays are over and give it another shot (at a much slower pace) in January. How did you determine what 10% was? Did you have to empty out the capsules? My goal is not to discontinue this medication, but to get down to 150 mg, stay there awhile and see how I do, then perhaps aim for 75 mg.

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