I had afib and also had the ablation procedure. I was put on eliquis after the procedure. Within two days of being put on 5mg twice a day I had leg muscle pain. Also could not talk because I coughed 24-7. Every time I tried to talk I coughed. My dr told me neither was a side effect I must take. After three weeks my legs and joints hurt worse and still the cough. I weigh 115 lbs. I decided to cut my pills in half. My cough was a little better and muscles still hurt but better. After two weeks I stopped eliquis and took a baby aspirin and vitamin e to thin my blood. No muscle pain or joint pain and my cough stopped. It mite work for some but for others it’s a poison. It’s called quality of life. Good luck.