This what I found
Many researchers believe it is caused cytokines; chemicals released into the blood by the body's immune system. When immune cells come into contact with leukaemia or lymphoma cells, they can release cytokines at high levels, causing irritation of nerve endings within the skin and thereby a persistent itch.
https://www.leukaemiacare.org.uk › ...
Can itchy skin be a sign of leukaemia?
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What is itching like with lymphoma?
CTCL-related itching is particularly vexing since it can start as a small fire and progress into a firestorm. An