After taking clindamycin for a dental procedure, my husband had a six month bout with c diff many years ago. After multiple courses of antibiotics and reactions to them, he put his foot down and refused to take any more. Finally, the GI doctor prescribed Questran, an anti-cholesterol drug that coincidentally binds matter in the intestines. Finally, after two weeks of Questran, he could live a normal life again. Sadly, his gut still reacts negatively to anything that disrupts the normal flora. He relies on kefir and other probiotics.
I haven’t read anything about Questran on these threads, but maybe it can help someone else.