No I was told by my ARNP that it would not show right away..My. bone density results are not as accurate as they can only take one leg as my other leg I had a broken knee and have a plate and screw..metal..THey took my. arms!Can only have every 2 years..I eat a very good healthy diet, take my vitamins and calcium I get from food and after concuring with my Neurosurgeon I recently signed up for exercise specific back execises with a DPT..I feel Tymlos worked and the concern of Causing Bone Cancer has been removed I was told after extensive studies of no Bone Cancer..The ARNP associated with Tymlos let me know when I was on my last dose! I did not have another choice my Neurosurgeon had seen "other back positive results to convince me..5 cracks was painfull I have never taken any drugs for anything unless it was necessary. I have osteoporousis and right now I am not interested right now in taking another drug for another 18 months and so on and so on. My Decision...right now! Hope this helps!