I recently read an article in the Harvard medical school report on P C regarding the use of enzalutamide and a new drug, talazoparib, and this has been given after the use of chemo and perhaps after or before Pluvicto. It is also given for breast and ovarian cancer. It may be something to chat with your oncologist about. Pluvicto and talazoparib may be drugs in my future. I am 1 year post RP and I had 13 months of ADT and Erleada. I am Gleason 9 aggressive advanced CRPC. Presently, my cancer is sleeping but who knows how long that will be the case. Good luck to us all.