Sigh..........My MRI was inconclusive as the doctor at City of Hope does not have the original PET scan taken at a different hospital (bureaucracies!!) and cannot tell if the brain lesion has gotten smaller or bigger. He says patience is called for as the imbruvica therapy can take 3-4 months to show any improvement. The MRI seems to have picked up more brain lesions than the written PET scan report. My daughter is going to the original imaging center tomorrow to pick up the CD and take it to my marvelous City of Hope oncologist. If the lesions are larger or more he plans to add another drug (cant remember the name but the side effects sound hellish). Today is Day 38 of being on the imbruvica and so far, no side effects.......oh bruising, but no big deal...... My stomach feels fine.......I'm tired and a bit loopy but it might be the brain tumors..........Cheers to all