Hi,
Many of you were recently discussing the effectiveness of vitamin B in reducing the symptoms of neuropathy. I showed your conversation to a pharmacist here at Mayo Clinic. She offered this information:

"Taking Vitamin B1 (thiamine) and Vitamin B6 (pyridoxine) daily has been shown in some trials to reduce symptoms of neuropathy. Other research suggests adding Vitamin B9 (folic acid, L-methylfolate) and B12 (cyanocobalamin, methylcobalamin).

- Vitamin B6 and B9 are well absorbed by tablet, capsule or injection. B6 can be administered with food to reduce upset stomach.
- Vitamin B1 is adequately absorbed in tablet or capsule form and rapidly and completely absorbed after injection into the muscle. The active metabolite of thiamine is pyridoxal-5-phosphate.
- Vitamin B12 absorption can vary from person to person, but is less well absorbed by mouth (tablet, capsule, sublingual) than the rapid and complete absorption after injection under the skin or into the muscle. Limited evidence suggests B12 nasal spray (Nascobal) achieves levels similar to injection into the muscle.

Befotiamine and methylcobalamin are marketed as dietary supplements. Metanx is a medical food marketed for diabetic neuropathy and contains L-methylfolate calcium (an active form of Vitamin B9, folic acid), pyridoxal-5-phosphate (an active form of Vitamin B6, thiamine) and methylcobalamin (Vitamin B12) along with algae-S powder. This is a medical food but is sometimes covered by insurance."

For those of you with good results in treating neuropathy, what products are you using?