Hi @lesliemont Starting treatment can feel pretty scary when you don’t know what to expect. I’ve been there myself along with so many others here in the forum. But we do what we have to in order to go on enjoying our lives.

The type of chemo you’ll be taking, just like @badnewsforme, will be on a cycle…usually monthly for the duration of the treatment.
First a little bit about the procedure. You’ll most likely be going to what’s called an infusion center. It’s generally a pleasant large room or private rooms in a cancer center clinic where other patients will also be receiving their infusions. This is all done by IVs. So you’ll have a small IV line put in, looks very much like the type you have when you have blood draws.
The IV solution is given slowly, especially with initial doses. It’s very common with the rituximab to have a little reaction the first time. But with these infusions, you’ll have a nurse right there with you so if you feel anything unusual let them know right away and they’ll push Benadryl into the IV and that calms the reaction right down.

The infusion areas are either in a large, pleasant room with lounge chairs or some places have private rooms. Everyone is there doing the same thing so sometimes it’s nice to have company. There’s always a TV but feel free to bring an iPad or tablet, (there’s always wifi). reader, books, knitting, etc. to help pass the time. The IV carts are battery powered so you get up to walk around or use the bathroom. None of it’s painful…just time consuming.

As the chemo starts working over the month between treatments you may start feeling very tired and not quite yourself. That’s ok it’s normal. The drug is killing off cancer cells but it’s not discriminatory so it will also reduce the number of red/white blood cells and platelets. 7-14 days after your last iv you may feel tired mentally and physically. That’s called the neutropenic or nadir period. This will be when your blood numbers are at their lowest. But then miraculous they start rebounding and you start feeling human again.

It’s very important during the months you’re in treatment to avoid getting ill. With your blood numbers down you’ll be very immune-compromised. Your body won’t be able to fight infections well. Basically, follow the strict Covid guidelines to help keep you safe. Wear a mask when you’re out in public, avoiding sick people, wash/sanitize your hands frequently. You’ll also have to be mindful of what you eat…avoid raw sea food, deli meats, no buffets or things like artisan cheeses that aren’t pasteurized. It’s also important to take your temperature daily and let your oncologist office know asap if it ever goes to 100.4. They will be watching for what’s called a neutropenic fever and want to know immediately if you do develop one. It would mean a trip to the hospital for antibiotic IV. (This is not meant to scare you…it’s something that can happen though so I want you to be prepared. I always kept a little bag packed with necessities for a couple day stay at the hospital).

I know, it’s a lot to take in, but you’re going to get through this one day at a time and then you’ll be able to get back to enjoying your life to the fullest.
Do you have a friend or family member who can go with you to your infusion sessions?