Side effects with omeprazole/Prilosec use

Posted by blueorca @blueorca, May 5, 2018

i am an 18-year user of daily OTC Prilosec. It does a perfect job of controlling my GERD but I am constantly battling side effects of nutritional deficiencies in iron, B-12, magnesium, etc. For example, my hair is extremely thin and loss of energy is a constant problem. I am looking for specific help in knowing which supplements to take for this and in what doses and formats and on what schedule. All the nutritionists I've found locally are not well-versed in Prilosec use. Is there a medical provider out there who specializes in this? And would they be willing to work with me long distance?

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Profile picture for Jacki @jaxtapoze

I had no clue that Pantaprazole had the horrible leg pain side effects. I too wake up in such excruciating pain that it takes my breath away. My dr only told me to take Magnesium but nothing about WHY I was going through Hell every night, I just thought it was horrible neuropathy! Thanks for sharing

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If it is leg cramps you are having, if you haven't already, try yellow mustard - I know it sounds crazy but it works, one teaspoon before bed !!! OR when you get them, take some and within 2 min. should subside. !!! someone told me about it and I too didn't believe him, but Google it !!!

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Profile picture for dedhambeth @dedhambeth

I have been reading the here about the long term side effects of omeprozole and am going to try to wean off. Suggestions? Thanks!

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In my experience, going off the PPI also required dietary changes. I went cold turkey since the GI who did my endoscopy told me to stop and never take again due to my cells being hypertrophic (very enlarged).
I immediately went gluten free, dairy free, sugar free (use organic stevia now), alcohol free, and switched to a low acid coffee. After 2 weeks I started feeling immensely better. Short version of my journey: After some testing, I learned I was gluten intolerant, had SIBO, a yeast infection and reacting to mold. I consulted with a nutritionist at my doctor’s office and she guided with foods to omit while my gut healed. And foods to definitely add to my diet.
Getting off a PPI can be done with the right help.
Best to you, I know it’s not easy.

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Profile picture for rosemaryhow @rosemaryhow

I have been on a PPI now ( prilosec) for probably 20 yrs. It began back when they believed there were no significant side effects. Then a study was done stating of really significant side effects.I tried desperately to get off of it--weaning down on the frequency and dose, then stopping it. I was so ill I could not eat. Lost 20#. GI doc told me to get back on it. Since then I have developed this LPR thing, and am trying to accept this as my life now. I wish I would have made it off the drug. At least now they know that when they put a patient on a PPI. It should only be for a limited time.

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rosemaryhow, what is LPR?

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Profile picture for t98 @t98

@drrobertsmsmft Nexium is also a PPI like omeprazole

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Yes, it was prescribed by my doctor but was not covered by my insurance. When it came on the market as an OTC, my husband bought some for me. I learned about it and, by then, I was on the way to getting my LINX procedure.hope that helps you to understand my journey.

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Profile picture for marjoriem @marjoriem

rosemaryhow, what is LPR?

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So when I was having problems breathing thru my nose and went to my primary care doc, and we it was assumed was a chronic sinus issue, she sent me to see ENT who is suppose to be a sinus specialist. I have had GERD for many years, but had it under control, and was pleased for that. But ENT doc looked at my sinus x-rays which said that my sinuses were narrowed and almost completely occluded, and his statement was that "he was not impressed" . He did not even do any exam. He handed me a brochure on Laryngeal,Pharangeal,Silent Reflux and said this is a GI problem. Go back to GI. So I did. Evidently ENT says that refux from your gut comes up and can go all the way up into your sinuses causing occlusion. My GI docs act like there is no such diagnosis. They just keep wantin to increase the dose of the PPI. If you google LPR you can read what the term means, and it does not sound to me that all medical people are in agreement with the Dx.

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Profile picture for rosemaryhow @rosemaryhow

So when I was having problems breathing thru my nose and went to my primary care doc, and we it was assumed was a chronic sinus issue, she sent me to see ENT who is suppose to be a sinus specialist. I have had GERD for many years, but had it under control, and was pleased for that. But ENT doc looked at my sinus x-rays which said that my sinuses were narrowed and almost completely occluded, and his statement was that "he was not impressed" . He did not even do any exam. He handed me a brochure on Laryngeal,Pharangeal,Silent Reflux and said this is a GI problem. Go back to GI. So I did. Evidently ENT says that refux from your gut comes up and can go all the way up into your sinuses causing occlusion. My GI docs act like there is no such diagnosis. They just keep wantin to increase the dose of the PPI. If you google LPR you can read what the term means, and it does not sound to me that all medical people are in agreement with the Dx.

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Rosemaryhow, The problem with specialist is, they don't look outside the box. They are so narrowminded with their own little specialty and will not look beyond it. It's really awful!

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Profile picture for dedhambeth @dedhambeth

I have been reading the here about the long term side effects of omeprozole and am going to try to wean off. Suggestions? Thanks!

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To me, PPIs are as bad as opiates. Provide a lot of relief but very difficult to get off and they have their own rebound effect. I have used it for a horse with Gastritis but I was in charge of how much he could take. I tapered him very carefully so he would have no withdrawal. Humans have to make their own decisions and often it is difficult. I would rather not start.

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Profile picture for dedhambeth @dedhambeth

I have been reading the here about the long term side effects of omeprozole and am going to try to wean off. Suggestions? Thanks!

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Dr. Jamie Koufman is a retired ENT who posts information on respiratory reflux. See if her postings help you: https://jamiekoufman.com. She says it's not a medical problem, but a management issue. I don't know if occlusions go away if you get the respiratory reflux under control. If you do get the RR managed properly, would you need surgery to open up the blockage?

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Profile picture for Drroberts @drrobertsmsmft

Yes, it was prescribed by my doctor but was not covered by my insurance. When it came on the market as an OTC, my husband bought some for me. I learned about it and, by then, I was on the way to getting my LINX procedure.hope that helps you to understand my journey.

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I just had my Linx removed they now know it builds up scar tissues and it stopped functioning causing ulcers and esophagustis. Now back on PPI's so will have to have a major diet change.

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Profile picture for Drroberts @drrobertsmsmft

I went off omeprozole and started taking NEXIUM when it became available OTC in 2014. I had no problem.

What really helped me in the end was having a LINX Augmentation device placed in 2018. I was having acid reflux 84 times a day and nothing was helping. Since the procedure and a hernia repair I have not had any problems. Please research this solution. Best to you.

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I had my Linx in 2014 and worked great until it didn't, just had it removed last week due to scar tissues and failed, ended up with stage C esophagitis ad ulcers, so back on PPI's again. I guess strict diet will be the only thing that works!

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