I increased from 5 to 10 mg but am now considering surgery. The 10 mg felt great for a while but the echos never showed the kind of improvement some very lucky patients have experienced. My gradients have been all over the place from 60s to 227. However I also have serious bradycardia and 'eccentric' mitral valve regurgitation which complicates things. I am 71 and petrified of surgery but occasionally feel so weak that I can't walk. The pounding heart, head rushes, hot/cold sensations are no way to live. There's no predicting when these will occur so I stay close to home. I can be well enough one minute and grasping furniture to stay upright the next. I appear to be an outlier so don't base any decision to ask for a higher dose on my experience. Very best of luck to you.