Hi, I am 39. Off the charts on the EBV markers. I had mono around age 13. I'd say most of my adult life I've struggled with extreme fatigue, the inability to heal from even simple things like minor cuts and scrapes. I kept getting written off by general drs as I am deemed "fit and healthy". I raised enough hell about 2 yrs ago after my dr had mentioned to me that routine blood work came back with positive ana still. She finally referred me to a Rheumatologist who I am beyond grateful for everyday. Turns out I am off the charts for both EBV and for Rheumatoid arthritis. This has explained so much for me. We've been going through diff meds which was the hardest part but think we've finally found the one that is for me (Rinvoq). I finally get very minimal flare ups and have learned some helpful natural things to keep flares at a minimum the most important of course is rest. I can't handle any of the antiviral meds they try me on for the EBV but have found being treated properly for the RA has me feeling better than I have in decades. The fatigue is still the only nagging problem but I do have a medication for that I try to take it every other day to keep from getting too used to it. Its been a game changer. I have read tons about both disorders and have read that unchecked EBV can activate and cause auto immune disorders (my RA).