Probability of passing on Von Willebrand's

Hello @abbiem Von Willebrand’s is primarily an inherited disease caused by genetic changes that are almost always inherited (passed down) from a parent to a child.

The Center for Disease Control and Prevention has some very informative articles regarding Von Willebrand’s disease.
I’ve posted two links below. The first discusses VWD and facts about the disease.
The second article explains the genetics behind inheritance of the disease.

This is an excerpt from the first article. (The link is directly below the excerpt)

“Most people who have VWD are born with it. It almost always is inherited, or passed down, from a parent to a child. VWD can be passed down from either the mother or the father, or both, to the child.

While rare, it is possible for a person to get VWD without a family history of the disease. This can happen if a spontaneous mutation occurs. That means there has been a change in the person’s gene. Whether a child receives the affected gene from a parent or as a result of a mutation, once the child has it, the child can later pass it along to his or her children.

Also, it is rare, but possible, for a person to get or acquire VWD (they didn’t receive the affected gene from their parent or as a result of a mutation) later in life because of an underlying medical condition. This can happen when a person’s own immune system (which controls the body’s ability to fight germs and sickness) destroys his or her VWF, often as a result of the use of a medication or as a result of another disease. If VWD is acquired in this way, it cannot be passed along to any children.”
https://www.cdc.gov/ncbddd/vwd/facts.html
On inheriting the disease:
How von Willebrand Disease Is Inherited
https://www.cdc.gov/ncbddd/vwd/inherited.html
Do you have VWD or know of a family member who has it?