Hello, I've had an EBNA of over 500 and in general felt terrible with severe fatigue. Eventually, I got a prescription for valacyclovir 3g daily, and over the course of 9 months, my levels dropped from over 500 to the 280 range.

This is the only antibody that had a response while I was on the medicine. I did have to go back onto 1g as some symptoms started to return but it resolved it over the course of about 4 months. I think I may need a daily of 500 to maintain instead of going cold turkey but I'm still on the 1g for now. I included the chart of how my EBNA levels dropped.