1. < Heart & Blood Health

Carvedilol & antidepressant

Posted by loveitaly @loveitaly, Apr 12, 2023

Just joined. So glad I found this group! I am taking 25mg of Carvedilol twice a day. I have been taking Duloxetine for depression and anxiety for years. My anxiety has been getting bothersome for a couple of months and my depression is bothering me a bit. Does anyone have experience with taking an antidepressant that can be taken with Carvedilol?
Thanks.

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Mentor
Ginger, Volunteer Mentor | @gingerw | Apr 13, 2023

@loveitaly Welcome to Mayo Clinic Connect! Sometimes we need to modify our medications when we start a new regiment. It's so important to let our providers know all the medications we are taking. Also, a brick-and-mortar pharmacy can be a great source for information on your prescriptions and interactions, including when to take them to reduce cross-interactions.

Here is what drugs.com has to say about carvediloll and your antidepressant together: https://www.drugs.com/drug-interactions/carvedilol-with-cymbalta-531-0-949-2273.html#:~:text=DULoxetine%20may%20increase%20the%20blood,to%20safely%20use%20both%20medications.

Have you discussed the two drugs with your providers, yet?
Ginger

REPLY
stardiamond1223 | @stardiamond1223 | Apr 17, 2023

This question is about carvedilol. I have been taking this med for about 6 years. I had a heart attack back then and was put on carvedilol along with brilinta because I am allergic to aspirin. I felt fine. About 2 years I had more blockages and now I have 9 stents. I feel awful, so weak, diarrhea, and I am lightheaded all the time and very off balance. I think it is the carvedilol, but none of my doctors seem to care about what I am saying, they keep telling me it is the best med out there for my heart and blood pressure. I also take insulin, protonix, furosemide and Lipitor. I am worried about what else has been happening to me, the bottom part of my blood pressure is staying at 58, and that is without the carvedilol? Thanks for listening.

REPLY
1 reply
Moderator
Colleen Young, Connect Director | @colleenyoung | Apr 20, 2023
In reply to @stardiamond1223 "This question is about carvedilol. I have been taking this med for about 6 years. I..." + (show)
@stardiamond1223

This question is about carvedilol. I have been taking this med for about 6 years. I had a heart attack back then and was put on carvedilol along with brilinta because I am allergic to aspirin. I felt fine. About 2 years I had more blockages and now I have 9 stents. I feel awful, so weak, diarrhea, and I am lightheaded all the time and very off balance. I think it is the carvedilol, but none of my doctors seem to care about what I am saying, they keep telling me it is the best med out there for my heart and blood pressure. I also take insulin, protonix, furosemide and Lipitor. I am worried about what else has been happening to me, the bottom part of my blood pressure is staying at 58, and that is without the carvedilol? Thanks for listening.

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@stardiamond1223, you may also be interested in this related discussion:
- I'm starting carvedilol. What are your experiences? https://connect.mayoclinic.org/discussion/new-drug/

You are taking quite a few medications and it might be helpful to request a medication reconciliation with your pharmacist. They can review all your meds and may suggest possible causes for your symptoms. See this related discussion:
- Medication reconciliation: Who do I talk with to review all my meds? https://connect.mayoclinic.org/discussion/stop-all-medicine/

@loveitaly, how long have you been on Carvedilol? Have you discussed potential drug interactions with your pharmacist?

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