1. < Digestive Health

Anyone on or have taken Motegrity?

Posted by januaryjane @januaryjane, Feb 22, 2020

Anyone on or have taken Motegrity?? I am on it, 3 months, and just wanting comparisons/advice. Im taking it for stubborn CIC (slow-transit).

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sickofbeinsick1. AKA Tina | @sickofbeinsick1 | Oct 21, 2022
In reply to @jbon8 "I take Motegrity for my SIBO, I am also constipated. It is my understanding that you..." + (show)
@jbon8

I take Motegrity for my SIBO, I am also constipated.
It is my understanding that you need to give it a two week break every 3 months ( your body gets use to it)
Have you tried Magnesium citrate or glycinate?

Jump to this post

Magnesium Citrate helps me…MoM gives me MAJOR gas

REPLY
notmoff | @notmoff | Oct 22, 2022
In reply to @jbon8 "I take Motegrity for my SIBO, I am also constipated. It is my understanding that you..." + (show)
@jbon8

I take Motegrity for my SIBO, I am also constipated.
It is my understanding that you need to give it a two week break every 3 months ( your body gets use to it)
Have you tried Magnesium citrate or glycinate?

Jump to this post

I take Vitacost's 400 mg magnesium citrate at night with calcium, and vit D for my bones. It helps with my obstipation. How to balance the constipating effect of supplemental calcium with its also being necessary for bone strength is challenging.
My GI rx Motegrity, but I find occasional Miralax and a stool softener plus enjoying plenty of fall fruit is working for the moment.
Can you say more about the quarterly 2 week break from Motegrity?

REPLY
1 reply
jbon8 | @jbon8 | Oct 22, 2022
In reply to @notmoff "I take Vitacost's 400 mg magnesium citrate at night with calcium, and vit D for my..." + (show)
@notmoff

I take Vitacost's 400 mg magnesium citrate at night with calcium, and vit D for my bones. It helps with my obstipation. How to balance the constipating effect of supplemental calcium with its also being necessary for bone strength is challenging.
My GI rx Motegrity, but I find occasional Miralax and a stool softener plus enjoying plenty of fall fruit is working for the moment.
Can you say more about the quarterly 2 week break from Motegrity?

Jump to this post

Got my info from Dr. Mark Pimentel’s book “ The Microbiome Connection”. He addresses the issue of prucolapride may lose effectiveness after a few months and to go on a “drug holiday” on page 111.
I highly recommend his book!

REPLY
heyjoe415 | @heyjoe415 | Dec 1, 2022

Can I take Motegrity with Citrate of Magnesium? Thx all! Joe

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heyjoe415 | @heyjoe415 | Apr 16, 2023

Hi everyone. I'm a 68 y/o male with CIC. After trying everything (and I'm active, at the gym 6 days/week), nightly Miralax followed by bisacodyl every three days does the trick. This has been called the "Mush and Push" approach.

My concern is taking bisacodyl regularly. I've read that it will damage the colon's natural motility, but have seen no studies proving this. Anyone have any feedback? Mag citrate also helps but is hard to manage. Thanks all! Joe

REPLY
catmomma | @catmomma | 8 hours ago

Hi,

I am on Motegrity for gastroparesis and intestinal failure (lack of motility throughout my whole GI tract). And any medication I take makes it worse. Fortunately, I have had great luck with Motegrity-I see GI in Rochester (about 3 hours from my home), and they recommended this-as I didn't do well on Reglan and pretty much every OTC and prescription medication I have tried has either not worked or caused intolerable side effects.

The flip side is due to the expense, I have been on and off of it for 2 years due to insurance and/or lack of it. I have great insurance now, and will continue to have it, so I am back on it and it's going pretty well. And without the side effects of the other meds I have been on for this. With the gastroparesis I have been on nutrition support (tube feeds and TPN), so this has been a real blessing!

Hope this helps.

REPLY
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