Anyone on or have taken Motegrity?

Posted by januaryjane @januaryjane, Feb 22, 2020

Anyone on or have taken Motegrity?? I am on it, 3 months, and just wanting comparisons/advice. Im taking it for stubborn CIC (slow-transit).

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@jbon8

I take Motegrity for my SIBO, I am also constipated.
It is my understanding that you need to give it a two week break every 3 months ( your body gets use to it)
Have you tried Magnesium citrate or glycinate?

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Magnesium Citrate helps me…MoM gives me MAJOR gas

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@jbon8

I take Motegrity for my SIBO, I am also constipated.
It is my understanding that you need to give it a two week break every 3 months ( your body gets use to it)
Have you tried Magnesium citrate or glycinate?

Jump to this post

I take Vitacost's 400 mg magnesium citrate at night with calcium, and vit D for my bones. It helps with my obstipation. How to balance the constipating effect of supplemental calcium with its also being necessary for bone strength is challenging.
My GI rx Motegrity, but I find occasional Miralax and a stool softener plus enjoying plenty of fall fruit is working for the moment.
Can you say more about the quarterly 2 week break from Motegrity?

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@notmoff

I take Vitacost's 400 mg magnesium citrate at night with calcium, and vit D for my bones. It helps with my obstipation. How to balance the constipating effect of supplemental calcium with its also being necessary for bone strength is challenging.
My GI rx Motegrity, but I find occasional Miralax and a stool softener plus enjoying plenty of fall fruit is working for the moment.
Can you say more about the quarterly 2 week break from Motegrity?

Jump to this post

Got my info from Dr. Mark Pimentel’s book “ The Microbiome Connection”. He addresses the issue of prucolapride may lose effectiveness after a few months and to go on a “drug holiday” on page 111.
I highly recommend his book!

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Can I take Motegrity with Citrate of Magnesium? Thx all! Joe

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Hi everyone. I'm a 68 y/o male with CIC. After trying everything (and I'm active, at the gym 6 days/week), nightly Miralax followed by bisacodyl every three days does the trick. This has been called the "Mush and Push" approach.

My concern is taking bisacodyl regularly. I've read that it will damage the colon's natural motility, but have seen no studies proving this. Anyone have any feedback? Mag citrate also helps but is hard to manage. Thanks all! Joe

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