I tapered from 75 to 37.5 last summer, no withdrawals until I had been on 37.5 for 2 weeks (this was 8 weeks after starting the taper). I went back to 75 and eventually increased to 150mg. This was not good but I gave it 3 months. I cut back to 112.5 for 10 days, 75 for 10 days, 37.5 for 10 days and then stopped. I started 30 cymbalta right away, two weeks later I started 60 mg. So far no side effects. I hope this is the answer. I didn't know they can stop working and would have stayed on effexor forever. I felt great on it until I got covid.