Hi Judy, to eliminate the bone pain from Neulasta Injections, oncology teams usually recommend Clairitin, the over the counter antihistamine. (Not Clairitin D). One capsule or tablet per day beginning the day of the injection and take at least 7 days. It works! Ask your husband’s doctor if it’s ok for him to take it. It works!!

You’ll see it discussed in the coversations below.
https://connect.mayoclinic.org/discussion/bone-pain-from-nulasta/

My Oncologist put me on Claritan. One softgel daily. It is working beautifully. I don’t understand how a Anti-Allergy over the counter can work so well, but it does. I’ve had three Neulasta shots and bone pain is un- noticeable.