I everyone, my name is Steve from Sydney Australia. I have just stumbled upon this site after spending an hour with my Hematoglist this morning. I have had PV since 2010. I am 60 years old. I have never really spoken to anyone about my condition except my beautiful wife. But after this morning I just feel that I need to share and start some serious researching. I have basically had my PV under control for the past 10 years but lately my platelet and white blood cells have risen from their normal highs and my doctor this morning wanted to start me on a new treatment (Peginterferon alfa-2a injections) to work in conjunction with my current regular medication which is Agrylin. But after researching over the past two weeks and our discussions this morning I am not sure I wish to proceed. Anyway, there is so much I wish to share and talk about, maybe another time. Just one thing she told me this morning that they (doctors) don't know what's causes the Jake 2 mutation. And I am interested in the Vitamin D 3 research. thanks, and take care everyone, steve