Success with Prolia?

I started Prolia 10 months ago. I wondered if you would share how much you improved each year on Prolia?

I had my first injection of Prolia at the end of August 2022. I had serious reservations, but my orthopedic doctor said any pharmaceutical has a list of side effects that would scare the pants off you, yet very few people ever experience the bad side effects. Two things she didn't say was that Prolia is an immuno-suppressant and the other is that I will have to take it for the rest of my life. After I got the shot, she talked about the length of time I would be taking it and she stopped about 85 years old, which means she estimates I will only live another 17 years. I have been having fungal infections for the first time in my life that I cannot seem to get rid of. I don't want anymore pharmaceuticals, ever. I want to stop Prolia. I will see an endocrinologist as soon as I can get a referral to determine the best way to stop. I also have some dental problems that started after the shot, coincidence? I am very disheartened at this point and feel I've been lied to by all concerned.

-2.8 2018; -2.7 2019; -2.7 2020; -2.6 2021; -2.5 2022
I hope this helps

I’m sorry to hear that- my endocrinologist said you could take a Reclast yearly infusion instead.
Also, I read that just one Prolia and switching to another osteoporosis drug doesn’t lead to increased/rebound fractures that can occur. That happens if you stop Prolia and take nothing else.

Thank you leslie2121. I appreciate hearing that. I also appreciate seeing @pami results with Prolia. Some real life positive experiences with this drug are very helpful.

Just want to comment that that rate of improvement, as show by @pami, is not sufficient for those of us with worse scores 🙂 But good for maintenance after bone building meds.

My lumbar t-scores

July 2019, age 50, -3.9
July 2021, age 52, -3.7
December 2022, age 53, -3.6

I also have Hashimoto's thyroiditis which caused hypothyroidism. Was diagnosed with this in 2017, age 48, and I take 75 mcg of levothyroxine daily for this.

For my osteoporosis, at my endocrinologist's recommendation, I took alendronate from January 2020 to July 2021, and quit taking it because it was causing digestive tract issues. Then my endocrinologist pushed me to have a zoledronic acid infusion, he told me my bones were "horrible" and not knowing what else to do, I had the infusion in November 2021.

After having the infusion, I started doing my own research and discovered that my endocrinologist wasn't doing what he should have done. He hadn't ordered any tests to rule out secondary causes and he had never even looked at my full DEXA reports. All he was basing his decisions on was my DEXA summaries.

When I finally got my hands on my complete DEXA reports from July 2019 and July 2021, I discovered that the "big gain" in my left hip was really a big gain, it appears to be an error in my July 2019 report that made my left hip look worse than it actually was.

My endocrinologist expected me to have another zoledronic acid infusion this past November, but I have put it off. I need to find a doctor who can actually tell me what my bone turnover marker tests mean before I take any more osteoporosis meds. All the reading I have done on this topic is making me think that my hypothyroidism is what is effecting my bones.

My doctor wants to put me on Evenity but im concerned about the possible cause of stroke. Since I have a PFO ( hole in my heart ) im more concerned. He said if I didn’t want to start Evenity I can go on prolia but it’s not as good. Is there a better treatment than prolia? I was only on fosomax for a month.