Welcome @msipma. I'm tagging @f019521 and @gingerw to make sure that they see your post.

What treatment will you get starting for monoclonal gammopathy of renal significance (MGRS)?

Greetings! I spent a good deal if my life in Spearfish. Where are you going for treatment?

Patty

@msipma Let me also add my welcome to Mayo clinic Connect!

MGRS is not a common condition to have, but it is manageable. If you read my reply above to @f019521, there is some practical information about living with compromised kidneys. Everyone is different, and you'll want to get as much solid information from your medical team as you can. If you have existing co-health issues, everything, and all your specialists, will need to be on the same level of communication with you and each other! That is critical.

I found this article from Tufts University. The top part gives some additional information for you on this MGRS.
https://www.tuftsmedicalcenter.org/patient-care-services/departments-and-services/cancer-center/clinical-care-services/myeloma-and-amyloid/mgrs
Ginger

I was diagnosed last fall, I had done 4 months of chemo and go next week to do stem cell collection. I've pretty well so far

I was diagnosed with MGRS in December 2023. Just completed 26 weeks of Chemotherapy (CyBorD) treatment. My kidney function is now normal, and my blood and urine labs are mostly in the normal range. Hemoglobin is still low (10.2-10.8) but my doctor thinks this will improve over time. Side effects from chemo were mild (loss of taste, diarrhea, tiredness) all of which were temporary. My doctor did give me the option of continuing treatment since there is little experience treating such a rare condition and the abnormal proteins are still detectible. I opted to take a break, and we will continue to monitor my blood and urine on a monthly basis. I would be interested in your experience with this condition and your treatment plan. Hope all has gone well for you. Best Wishes, PJP