As you've probably read by now, there really isn't a cure for GD, only a bunch of creams, etc that help some people and no one reacts the same. Some of the treatments we tried were at my request from reading about it on this site. For me the only cream that gave me some relief was Clobetasol, but being a steroid it can't be used constantly. I've suffered for over a year, head to toe and scratched until I bleed leaving me with scars that may never disappear. About 6 months ago my dermatologist tried Prednisone for an approximate 3 week period. It gave me nearly instant relief until I was down to 2 pills a day and I started to itch once again. Since it had somewhat helped, we tried again and so far so good. I'm taking 10 mg tablets: 7 days-4 tabs, 7 days-3 tabs, 14 days-2 tabs, 14 days-1 tab and then 1 tab every other day for 3 weeks. Right now I'm starting the 1 tab every other day and still don't itch. Maybe it did reset my immune system or maybe I was entering a remission period anyway and this just helped me get there. I know it never really goes away and could come back at any time, but for now I don't itch and I'm doing everything to help heal my skin before it all comes back again. I'll post again as I complete my treatment and whether I start to itch again. Please keep up posted on how you are doing.