Anyone have experience with Low Dose Naltrexone instead of prednisone?

I am not sure what my dosage was as it has been several years since I took it. It seems like it was 50 mg. I don’t know the other things it was compounded with. I don’t normally take opioids either, but I had knee replacement last year and several bad falls where I messed up my face and mouth. I did take them for awhile with all of those. Hope not to have anymore bad falls.

LDN
Anyone have info on this for treatment of PMR?

Hello @novkgen, Welcome to Connect. You will notice that we moved your post to an existing discussion on the same topic here:
-- Anyone with experience using Low Dose Naltrexone?
https://connect.mayoclinic.org/discussion/anyone-with-experience-using-low-dose-naltrexone/
Are you considering LDN instead of prednisone for your PMR?

I would be interested in trying it.

Glad to repeat my experience about LDN. I consider it a miricle drug for me but others have had no effect. But the only side effects can be vivid dreams so worth a try. I had two types of pain when I was waiting to be diagnosed for PMR. Pain when I used my muscles and pain when I wasn't moving. (Trying to sleep.) The LDN (2 mg) stopped the not moving pain in two days. Much like pred can do when it works. (Without the side effects.) When I went off of it for awhile, when I had my hip replaced (I was on opiates) after 3 weeks, the all over pain came back. I got back to the LDN as soon as I could. It also helped my small intestine heal from the small ulcers that were plagueing me. (I have Crohn's.) So, great drug but probably not a replacement for pred with PMR. I use them both. Lots of on-line research. Look at it.

Yes I have been on LDN for about 30 days now. It has helped a good deal not only with PMR stiffness my anxiety and mental focus seem to be better as well.
I was feeling good enough to stop steroids, but after a few weeks I expectancies swelling in knee an old injury that not flare along with PMR so I’m back in 5mg steroids and will tapper after 30 days.
I was advised that LDN can continue to help improve symptoms more with time.
Good luck to you!

I just started taking it today for itchy petechiae that developed nine months ago and has not improved,

Let us know what you experience.

It’s been four days, and I think Naltrexone is a wonder drug! My rash is still there, but the itching has almost completely stopped!

There are side effects to this drug. I have insomnia, and a bit of a stomachache. It also is supposed to kill your appetite. Mine was already dead, so I can’t tell the difference,

Your side effects are interesting as I experienced none of that. Just vivid dreams that were like Broadway musicals. Lots of color. Miss them since they stopped. But I was underslept because of pain which it stopped. I think it is a wonder drug, too.