MTHFR mutation and supplements to take

In addition to Heterozygous MTHFR C677T, I have Sjogren's Disease. I am specifically concerned about the connection to non-Hodgkins Lymphoma, of which my father died at the age of 41. Additionally, my mother died of Ovarian cancer (age 67), paternal aunt from Breast Cancer, age 66, brother from Liver cancer age 61, other brother survived prostate cancer.
I have gluten allergy, lactose intolerance, osteoporosis, high cholesterol (313, being treated with Simvastatin and Ezetimibe).
I do take supplements and jog 7 miles a day.
I am 5' and weigh 99 lbs.
Female , Age 70
Throughout my life, I have had repeated re-occurrences of laryngitis which turn into pneumonia.
With Sjogrens and Heterozygous MTHFR C677T, what should I be doing to stay healthy, especially in the winter months.
The Sjogrens has exacerbated causing wacko temperature swings and I often go from feeling freezing cold to burning hot within minutes.
I try to stay away from anyone sick as these auto-immune diseases wipe me out when triggered.

Hi ! I am new to the post and community here. I came across this while searching for the MTHFR mutation. All I was told by my gp was I have the mutation but homocysteine is within range and bit b12 is high. Which is due to the mutation . He’s thinking Hashimoto (?) . Any advice - Ty in advance!

Can anyone recommend drug/drugs that may be helpful in tapering off of Tramadol?

I have this and so does my adult son. For my case and his, our diet had to change big time. I also have had my thyroid removed and parathyroid many years ago as it was so unstable. Synthroid ever since so I could check that box off. The covid shots through my body into a mess, and my son and I both had huge reactions. MTHFR was mentioned to both of us in two different states. We both ended up with holistic medicine doctors to deal with Mast Cell Activation and the supplements required to correct out chemistry . Their protocols were excellent. Take a look at Becky Campbell’s amazing site, and Beth O’Hara’s.. There are many sites around the entire world for MCAS . I use Becky’s supplements called Optimal Reset, and they are a Godsend for correcting . MTHFR is very good at causing weird upsets! I react to everything and have a long allergy list. My adult son actually went into anaphylactic shock from it after one of his covid shots. I was very sick after each shot. I hope you check out the web sites for MCAS and see if that has any ah ha moments for you! Good luck!

I have MTHFR from mom and dad. Does it have to be from both or can one parent have te gene?

Hi everyone, I tested positive for homozygous A1298C MTHFR. l am 56 years old and live in central FL. My whole life I have been plagued with sinus infections, chest infections, asthma. I feel like I am the healthiest unhealthy person in the world. Is it more helpful to see an MD or a nutritionist? Can anyone recommend a professional in central florida who knows how to treat this? Thank you.

I think it's from both parents, but only my Dad had mthfr. I have double 677 variant. Getting answers for help is very difficult. Mds not familiar with it. I take methyl folate and vitamin from Methyl Life. They are most knowledgeable about mthfr

I will definitely check out sites you mentioned. Thank t soooo much! Hope you and your son are feeling better 💙

I have been taking B12 shots for about 2 years, have mthfr double 677 variant, celiac, neuropathy, hashimotos. Due to celiac I don't absorb B12 pills. You don't want synthetic B12 shot, it contains arsenic. Am still searching for help with mthfr.

My b12 was over 2,000 but lab shows how much B12 in body, does not show how much is usable so test is not correct. I take daily b12 shots and not synthetic kind, has to be Methyl type. That's great your homosysteine is ok.