Lupron killed my body's ability to produce testosterone. After about 18 months post Lupron my testosterone score remained at about 15 and was not Rising so my urologist put me on androgel, a testosterone replacement. This caused my breasts to enlarge so I stopped the testosterone replacement and later learned to prevent my breasts from enlarging they should have been radiated before I started the testosterone replacement. Now I will live with a testosterone measurement of about 15 for the rest of my life and be fatigued and tired. Yet, the benefit is that I'm less likely to have a prostate cancer recurrence because of the low testosterone.