Regarding Prunelax, the active ingredient is Senna which is a stimulant laxative, same as Senokot or generic brands. There is very little prune extract in Prunelax, some packages list plum extract content at .01 or .02mg which is little better than zero.

What more do you have to do. I suffer from this a lot. Magnesium citrate, liquid, helped me, but since the recall, there is none. It bums me out, because it would help me once in a while. I did get the fiber capsules, but I'm still backed up. Going to ask Dr maybe to increase my Reglan (sp)? The constant bloating just sucks. And honestly watch the water. I think the levels of chlorine they are putting in the water are hurting a lot of people's digestive systems, because it's poison. My water is so bad at my house, the city won't do anything but call the cops on me, while my health deterriates. And now have to pay culligan for safe drinking water for my family and pets. Just be careful. Stomach pills is a huge money maker. Any advice on being more regular would be helpful. I'm only taking 2 capsules a day, maybe I need more? It's the one with the phylum husks (sp).
Thank you and God Bless.
Gastrochic

Are you still on Mayo, reach out please I suffer severe colon motility.

Yes, I’ve had two years of every test you can think of. I failed everything. Went to pelvic PT for two years, visceral message, acupuncture and more.
I had all this in Boston and after two years they wanted to remove my colon. It’s been 5 years since it began due to cervical spine surgery. My bowels never woke up.
Yes, I’ve done every med possible. Both my pcp and Gastro think I should have them get together with notes and get me into Mayo. I’m 70 now and my regimen is quite severe on a daily basis and they think I need to get another opinion.

My symptoms is when I have more meat or cheese with no vegetables can make me constipation, I try to stay die with less meat or spicy food and eat the veggies that help me a lot, the best one are Beets, Broccoli, okra , carrots I am eating everyday, it helps me feels great.

All those clean-outs do not work for me, and many make me sick. Focus on food and supplements that help you poop. Regular medicines seem like a blunt instrument/dull tool for some of us. Go beyond them.

Have you tried Trulance..?? It worked for me.. Linzess didn't and Amtiza didn't.. I also take a dose of Miralax nightly if I need it.. and VSL3 probiotics...I drink 2 Vanilla Plant based Ensures every day (on Amazon) 5 mg fiber each and eat 1 Thomas multigrain English muffin with plant butter every day..(the wheat has sucralose. ..a good gut bacteria killer)..and am really careful about what I eat.. lots of water.. and prayers.. praying you'll find a solution!!

My wife has this and must have colonics even with every new laxative, it does not work
she went to a surgeon who said a ostomy is the answer but she refused this as she will not wear a bag.
Her issue they say is pelvic floor dysfunction and of course-constipation. Strange but that word does not really show how bad it is. Everyone gets constipated now and again but she is at another level.
Keep trying the new one's maybe it will work if not see a colorectal and see if anything can be done.

G