It worked quite well for me after I went thru the 1st 2 or 3 dozen treatments. *disclaimer: I only have neuropathy in my feet during the PM hours. Also, I got hurt in Viet Nam & many yrs later had 6 major back surgeries on my back & have a Medtronic Pain Pump in my body located left of stomach area. It has a catheter that carries the fentanyl from the Pain Pump into the spinal column where it sprays. I had the pain pump put in by my current Pain Dr. Jan 2018. Ron