I don’t think there’s any lasting issues with it. I didn’t really help me that much. Once in a while it seemed like I would get a little bit of remission but as soon as I started tapering it came running back. It’s supposed to help most people maybe I’m just the one off but I wouldn’t be too afraid of it. The steroid works in your intestines it’s not stomach. I did not have any side effects from it. Hope that helps!