Connect
TS-HDS Antibody and Small Fiber Neuropathy
Hello Everyone, I was wondering if anyone knows any information about the TS-HDS antibody test for neuropathy and what it means. After extensive testing, I had positive results for the antibody, and am dealing with small fiber neuropathy. If anyone has this antibody, can you recommend any treatments?
Like
Helpful
HugInterested in more discussions like this? Go to the Neuropathy Support Group.
Connect
Hi @lltripp2455, Welcome to Connect. Since you can post, you have officially joined Mayo Clinic Connect and are part of this and any group or discussion where you post. I'm glad that you are trying to learn more about your condition. That is a great first step. The two best reference sites I've found helpful for learning about neuropathy are:
-- Neuropathy Commons: https://neuropathycommons.org/
-- Foundation for Peripheral Neuropathy: https://www.foundationforpn.org/
You might also want to read through the following discussion to learn what others have shared helps them:
-- Member Neuropathy Journey Stories: What's Yours?: https://connect.mayoclinic.org/discussion/member-neuoropathy-journey-stories-whats-yours/
Do you mind sharing a little more about the symptoms that are the most troublesome and any treatments you have tried?
-
Like -
Helpful -
Hug
2 ReactionsI'd be happy to. I've had Peripheral Neuropathy since 2008 and it's been made tolerable with Gabapentin. I had a spinal cord injury in 2010 which created Cervical Myelopathy and again has been made tolerable with Balofen. Then in November I had a knee replacement. When in recovery I started having the severe pain (like I was having an EMG), severe burning and very severe nerve pain in all four extremeties. It began to improve some but at two months my knee replacement failed and I had to have a revision replacement. Coming out of surgery the pain was again VERY severe. My Neurologist drew the blood work for the TS-HDS and sent it to a lab in Minnesota (I think) an it came back showing the Small Nerve Fiber Neuropathy. So far nothing has been prescribed to help so I'm trying to see about supplements and possibly food triggers that make it worse. It ranges from 5-9 and sometimes I've even hit 10. I'm wanting ANY ideas people have for relief. Thanks in advance.
-
Like -
Helpful -
Hug
1 ReactionI’m not sure this is the right section to ask this question but…I have intermittent pain on the end of my big toe that feels like it is on fire (that’s the best way to describe it but the pain isn’t that severe). Does that sound like the initial stage of peripheral neuropathy?
Hi Rita @ritabtripp, It sounds similar to the pain I had with an episode of gout quite a few years ago. It started in my big toe on the right foot and gradually got to where it was difficult to walk. I was diagnosed with gout and given Colchicine which did the trick for me.
" Big toe pain is often the result of injury or minor underlying medical conditions. Arthritis, fractures, and gout may all cause big toe pain. Most cases of big toe pain are easily treatable with over-the-counter (OTC) remedies. However, some causes, such as sesamoiditis, may require more in-depth clinical treatment."
-- Big toe pain: 7 causes, other symptoms, treatment, and more
https://www.medicalnewstoday.com/articles/big-toe-pain
-
Like -
Helpful -
Hug
1 ReactionI had looked at that possibility but I wouldn’t think it is gout - it is the end of the toe and not the joint that is painful. Plus, I’m vegan so I wouldn’t think my diet would contribute to the problem. Does it sound like neuropathy?
It doesn't really sound like neuropathy if it's just the big toe. It sounds more like an injury that occurred and you were unaware of it but then I have no medical training. Have you discussed the symptoms with a podiatrist?
-
Like -
Helpful -
Hug
1 ReactionI'm getting a melisa test to test for a reaction to various metals. Titanium does well with this test where as the skin patch test does not work with Ti. Did you have this test also know as a LTT test it is out of a lab in Chicago. I got SFN 1 year after a hip replacement. I did have a very high rh factor too.
Hi. Yes, I did the Melisa test out of a lab in Germany. What is the LTT test? I got my implant removed a year ago and along with diet my symptoms have subsided quite a bit. Still get flares here and there. What are your symptoms?
Its pretty much the same test. Waiting on results. Hip transplant oct 2020 5 months out I had pain in the hip that i thought was the illiosopas however no real injury. 3 months later had unusual deeper pain in the hip when sitting or laying flat that went away when I lay on my stomach still have this pain. Jan 2022 weak legs ( lightheaded head aches tachycardia brain fog that only lasted a month) March 2022 the bottom of my feet started to burn lower hair started to fall out and puffy feet In May leg pain with weakness that's getting worse to today. I had a lot of strange things like 2 lumps wrist and shoulder in July 2021 and ruq pain (ct scan was good ) and bags under my eyes. Now my stomach started hurting a few months ago, eating a lot of eggs drinking raw milk avoiding spiced foods. The leg pain is the worst and the feet burn less at night, which is odd, not a major issue. What was ur neuropathy like ? Test results ? How high was the index on Ti ? Only neg. blood test high rh factor 146 125 96 (igg or igm) would like to have ts-hds done to narrow it down. Google titanium autoimmune disease second link is a good article. Oh and my shoulder hurts very sharp pain for the last year and arms fall asleep easier when just raised while sleeping. I'm a mess of pain but somehow happy that I can sleep well. What are the main differences post implant ? Thanks for ur input this is such a rare thing that all responses are very important for ppl with similar conditions.
Oh and one other question Carly was the neuropathy progressively worse up until the day you had the implant removed ? Mine surely is