Talicia for Helicobacter Pylori (H. Pylori) Infection

Posted by kidprodigy @kidprodigy, Sep 20, 2020

BACKGROUND:

I was diagnosed with a Helicobacter Pylori (H. Pylori) infection in my stomach back on July 1, 2020 after nearly a year of living undiagnosed and in constant pain.

Since receiving a diagnosis, I've taken multiple rounds of combination antibiotics therapy for my infection. They include:

2 x 14-day rounds of clarithromycin triple therapy (generic PrevPac)
2 x 10-day rounds of Pylera (bismuth quadruple therapy)
1 x 14-day round of bismuth quadruple therapy (generic Pylera)

Though my health has improved about 60%-70% since completing almost 9 weeks of treatment, I've decided to continue with therapy until the H. Pylori infection is fully eradicated.

My GI specialist just prescribed a 14-day round of Talicia therapy which I will begin taking tomorrow. Talicia was FDA-approved in 2019 and just launched in the US market back in March 2020 so it's a relatively new drug.

QUESTION(S):

1. Has anyone suffered from an H. Pylori infection? If so, what combination antibiotics therapy did you use to fully eradicate it?
2. Has anyone taken Talicia therapy? If so, was it effective and what were the side-effects?

Thank you for reading this post and providing your helpful feedback!

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Hi I have significant abdominal sensitivity and had a terrible reaction to one day of quadruple therapy. Wondering if anyone has been treated with IV antibiotics for hpylori.

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@mosey1

Hi I have significant abdominal sensitivity and had a terrible reaction to one day of quadruple therapy. Wondering if anyone has been treated with IV antibiotics for hpylori.

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Hello @mosey1 and welcome to Mayo Clinic Connect. I am sorry to hear about your initial reaction to your treatment, but am glad you're here to get support from other members!

I actually found an existing discussion on this topic so you will notice that I have moved your post here: https://connect.mayoclinic.org/discussion/talicia-for-helicobacter-pylori-h-pylori-infection/

I did this so you may more easily connect with members such as @riflemanz64 and @kidprodigy who have shared their experience in this discussion.

Are you being offered IV antibiotics?

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I had it back 2 or 3 years ago after going to digestive doc for 10 years with nausea , unable to eat hardly drink anything the last month my hair fell out . I requested Doc change he did endoscopy said must be meds but did not do biopsy, he retired so I got new Doc she heard my symptoms and knew right away did blood test positive , 2 antibiotics gone in few weeks
Symptoms went away I felt like new person I could eat nausea gone.
I am staring to have some stomach issues again going to ask for test be sure it’s eradicated. Great info it heard that kind of treatment
Mine was 2 antibiotics

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@amandajro

Hello @mosey1 and welcome to Mayo Clinic Connect. I am sorry to hear about your initial reaction to your treatment, but am glad you're here to get support from other members!

I actually found an existing discussion on this topic so you will notice that I have moved your post here: https://connect.mayoclinic.org/discussion/talicia-for-helicobacter-pylori-h-pylori-infection/

I did this so you may more easily connect with members such as @riflemanz64 and @kidprodigy who have shared their experience in this discussion.

Are you being offered IV antibiotics?

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Thank you. I am hoping to find out if treatment with iv antibiotics is available anywhere

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@mosey1

Thank you. I am hoping to find out if treatment with iv antibiotics is available anywhere

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Your GP or Gastroenterologist should be able to write out a special antibiotic regime to fix it completely. Over the last 40 years I have had it twice like this and it completely clears at that time.

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The gastro is suggesting a referral to discuss possible iv treatment options

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I am trying to find out if this treatment option might possibly be available at Mayo

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