Talicia for Helicobacter Pylori (H. Pylori) Infection

Posted by kidprodigy @kidprodigy, Sep 20, 2020

BACKGROUND:

I was diagnosed with a Helicobacter Pylori (H. Pylori) infection in my stomach back on July 1, 2020 after nearly a year of living undiagnosed and in constant pain.

Since receiving a diagnosis, I've taken multiple rounds of combination antibiotics therapy for my infection. They include:

2 x 14-day rounds of clarithromycin triple therapy (generic PrevPac)
2 x 10-day rounds of Pylera (bismuth quadruple therapy)
1 x 14-day round of bismuth quadruple therapy (generic Pylera)

Though my health has improved about 60%-70% since completing almost 9 weeks of treatment, I've decided to continue with therapy until the H. Pylori infection is fully eradicated.

My GI specialist just prescribed a 14-day round of Talicia therapy which I will begin taking tomorrow. Talicia was FDA-approved in 2019 and just launched in the US market back in March 2020 so it's a relatively new drug.

QUESTION(S):

1. Has anyone suffered from an H. Pylori infection? If so, what combination antibiotics therapy did you use to fully eradicate it?
2. Has anyone taken Talicia therapy? If so, was it effective and what were the side-effects?

Thank you for reading this post and providing your helpful feedback!

I had it back in 2018 and was put on 3 antibiotics which cured it. Not a big deal.

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I was wondering if the talicia helped you?? I’m also on talicia myself right now

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I also suffer from HPylori. I am not on this med but interested in responses to see if it helps

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@amandajean

I was wondering if the talicia helped you?? I’m also on talicia myself right now

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Hi! Since I posted this message I've completed 3 x 14 day rounds of Talicia. The side effects were minimal (less than what I experienced taking Pylera which contains that nasty metronidazole), my symptoms improved a good bit, and it's convenient to take in those bright orange-colored capsules.

However, even after taking 3x rounds of Talicia and many other PPI/antibiotics combo therapies, I'm still infected with H. Pylori. My symptoms persist and always worsen days/weeks after treatment ends.

I'm currently undergoing follow-up BreathTek urea breath tests (UBTs) and stool antigen tests as my GI specialist requires a positive result prior to prescribing additional rounds of treatment. So far, I'm having no luck turning up a positive test result even though I quit taking H. Pylori treatment (i.e. bismuth, PPIs, and antibiotics) back on January 1. What could I be doing wrong that might cause the UBTs and stool antigen tests to produce false negative results?

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So basically what you’re saying is all of your tests are coming back negative but you still feel as if you are positive?

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@amandajean

So basically what you’re saying is all of your tests are coming back negative but you still feel as if you are positive?

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Yes, that’s right!

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@kidprodigy

Yes, that’s right!

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Maybe an endoscopy that’s how they found my h pylori I believe it’s the most accurate way. I’m on day 14 of talicia and have some left side pain. Still with the heartburn if I test negative I think I will go see a naturopath for some supplements apparently they can help get your digestive tract back in line.

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@amandajean

Maybe an endoscopy that’s how they found my h pylori I believe it’s the most accurate way. I’m on day 14 of talicia and have some left side pain. Still with the heartburn if I test negative I think I will go see a naturopath for some supplements apparently they can help get your digestive tract back in line.

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Have you ever had an H. Pylori urea breath test or stool antigen test to confirm eradication post-treatment? If so, what were your test results?

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I was treated with amoxicillin-clarithromycin-lansoprazole for 14 days and that cured my H Pylori. I was tested for it during my EGD and it came back negative.

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@kidprodigy

Have you ever had an H. Pylori urea breath test or stool antigen test to confirm eradication post-treatment? If so, what were your test results?

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No this is my first round of talicia I will be retested in 30days with breath test

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