MTHFR mutation and supplements to take

Hello,

I am MTHFR (blood test level confirmed low Folate and DNA test), have high Ragweed Allergy (blood test confirmed) and Composite Mix II allergy skin test confirmed (I am unable to include links in my post as I am new here, but the information as to what this all means is below the the line____)

So I am limited to trying to eat certain things now... I was eating a lot of bananas and mangos, my favorite, including lettuce. The issue is that these things are all on my allergy list one way or another.

Is there a supplement that you would recommend? I take a lot individually, but that gets so expensive. A mayo doc suggested I cut back on all my supplements, which was strange as the only reason that I do this is because I have not found a solution in a multivitamin? That doc also said, "I have never met anyone with confirmed MTHFR". So I did not take her suggestion seriously. The mayo allergy immunotherapy docs spent less than 5 mins looking at my file, they never contacted me to discuss or look into things further... I was astounded and literally disgusted by their lack of help. I had to have additional testing with HealthPartners to figure out why I always feel sick.

I suffer from year-round stuffiness and eye itching. I am now on Zyrtec, Pepcid, Allegra, Singular, Flonase, Alaway, NasalCrom, and other medicines. These are just my allergy-specific ones.

High Prolactin, ADHD, and have an 8cm Bosniak 2F on my left Kidney. So I am trying to stay as healthy as possible.
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What are symptoms of ragweed allergies?
Like all pollen allergies, allergies to ragweed can lead to allergic rhinitis (hay fever), inflammation of the nasal passages.

Ragweed allergy symptoms are:
Nasal congestion
Runny nose with thin, water discharge
Postnasal drip
Sneezing
Coughing
Watery, itchy or irritated eyes
Eye swelling – the “allergic shiner”
Weakness or fatigue
Hives on the skin

What foods are related to ragweed?
You may need to avoid certain fruits and vegetables if you re allergic to ragweed and develop symptoms from eating these foods. This happens because foods botanically related to ragweed can trigger what is known as oral allergy syndrome (OAS).

Foods in the ragweed family include:
artichoke
banana
chamomile
cucumber
echinacea
mango
melon (watermelon, cantaloupe, honeydew)
sunflower seed
zucchini
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Complete list of categories in the Compositae Family:
Skin contact with Compositae Mix is required for it to cause a rash. Discontinuation of exposure to products containing Compositae Mix should result in improvement and/or resolution of your dermatitis. By law, all products made in the US for topical use have the ingredients listed either on the product package or the box that contains it, so check the labeling of your skin care products for this ingredient. If there is no information ask your pharmacist or call the company directly. At work, request a material safety data sheet (MSDS) to help identify potential sources of exposure. Personal care products that are label “botanical” may contain one of the ingredients of the Compositae mix.
African daisy
Arnica
Artichoke, globe
Artichoke, wild
Aster
Bitterweed
Boneset
Broomweed
Calendula
Capeweed
Chamomile, German
Chamomile, Roman
Chicory
Chickweed
Chrysanthemum
Cocklebur
Costus of perfumery
Cotton thistle
Dandelion
Elecampane
Encelia
Endive
Fireweed
Fleabane
Gayule
Groundsel
Hampweed
Helianthus
Hodweed
Inula
Ironweed
Laurel oil
Leafcup
Lettuce
Liverwort
Marguerite
Marigold
Marsh elder
Mugwort
Mutisia
Oxeye
Parthenium
Pyrethrum
Ragweed
Ragwort
Sagebrush
Sneezeweed
Sow thistle
Star thistle
Stinkwort
Sunflower
Tansy
Tulip tree
Whitewood of commerce
Wormwood
Yarrow

Hi @contilucy1960

My sister -in-law also has the MTHFR gene mutation and we were just talking about this question of know what to take this morning. I can confidently share with you that you can learn for yourself precisely what is right for you and for your body. How?

I teach every client self-muscle testing! This tool gives you the ability to listen to your body to know what is right for you. Everyone is different!

I don't tell my clients what to take. Rather I teach them how to do self-muscle testing and then give them a list of options and they find out what is right by listening to their body.

Everyone can learn how to self-muscle test. I and my clients use it every day for supplements, for food and for getting their best wellness.

Take care, Fred at The Wholesome Life.

I am compound heterozygous (heterozygous for each of c677t and A1298c), and have my share of symptoms, although nothing compared to homozygous c677t sufferers (mostly anxiety and energy in my case). I find there's a lot of bad information on the web, and am relying now on the Dirty Genes book by Dr. Ben Lynch, notably for which supplements to take and how to use them. I dislike his somewhat bombastic writing style, but he seems to be the only one I've found with accurate and thorough medical info. You have to be careful with supplementation for MTHFR; the wrong B vitamins (especially the wrong folate) can make matters worse, as can the wrong dosage, although I've found that dosages are something I have to arrive at by careful trial and error. Hope that helps. - Mitch G

Does anyone know what natural herbs and or oils to use? I’m type 2 diabetic and feel bad all the time and depressed.
MTHFR is the short name for it, even tho the short name seems WRONG! Thanks

Hello @sone63. Because you mentioned your interest in learning what herbs you may consider, you will notice that I have moved your post into this discussion on supplements for MTHFR mutation: https://connect.mayoclinic.org/discussion/mthfr-mutation-and-supplements-to-take

Do you currently take any supplements/herbs or use any oils?

I’m on prescriptions for HBP, Chl, I use frankincense,and others my wife is in to that.

Hello,

I was told by a pharmacist that the Orthomolecular supplements for the MTHFR are the best. Unfortunately, this pharmacy closed and now I have to find the medications elsewhere. I was taking 3 supplements: 1) Methyl CpG; 2) N-Acetyl Cysteine (NAC) but I cannot remember the other one. Would it be Methyl B Complex? Or is it Methyl B12? I would appreciate an answer. Thank you.

Laurie

Look at the Methylated supplements. Talk with your doctor and if he or she isn't helpful, find another doctor or call the Mayo Clinic directly. The supplements help a great deal.

I think it's methyl B complex. I had a great chewable from Amazon called EZ Melts I used to take. I have the MTHFR gene too.

Thank you for responding. From what I've been reading, the Methyl B12 is a better option.