Before my lung transplant, my pulmonologist reduced the amount of Pantoprazole that I was taking by prescribing Pepcid. I also had hiatal hernia repair (had a very large sliding hiatal hernia where the stomach attached to the left lung further complicating breathing) the year prior to my transplant. The transition from taking Pantoprazole twice a day to once a day replacing second time with Pepcid was an easy transition for me with no adverse effects. I have had GERD for so many years without relief that I have had 7 ulcers in my throat. However, the doctors don't know if the damage to my throat will ever fully heal even though I no longer throw up multiple times a day (no longer throwing up).
Since my transplant, I am only on Pantoprazole once a day and the acid is under control. So your doctors need to see what works best for you. Not everyone reacts the same way nor do you react the same way at different times.